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Showing 1 to 1 of 1 for “"multi-target antibiotics"”.
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Mechanistic investigations on polyprenyl transferases and multi-target antibiotic discovery
… head-to-tail prenyl transferases are druggable targets in antibiotic development. In Chapter 2, I discuss the new series of lipophilic bisphosphonates that inhibit the growth of various bacteria and target multiple prenyl transferases. To determine and verify the enzyme targets of antibiotic …