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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 12 of 12 for “"multi-omics analysis"”.

  1. A multi-omics analysis identifies retinol metabolism as a key pathway in wound healing

    Wüstemann, TillETH Zurich2024

    ethz Repository record

  2. Multi-Omics Analysis of 3D SKOV3 Ovarian Cancer Model Cell line Cultured on Novel Silicon-Titanium Diboride Micropatterned Substrate

    Amediku, Raphael 1994-University of Houston2026

    … on the culture platform. The transcriptomics analysis identifies significant alterations in genes associated with immune signaling, protease regulation was unique to day 7 versus control, cytokine signaling, controlled proteolysis, complement iii activation processes were overlapping …

    houston Repository record

  3. Models and tools for multi-omics analysis of non communicable diseases [Modelli e strumenti per l'analisi multi-omica delle malattie non trasmissibili]

    CAVALLARO, GIULIAUniversità degli studi di Catania2025

    … e strumenti per analizzare facilmente i dati multi-omici relativi alle malattie non trasmissibili. Pertanto, in questa tesi introdurremo i seguenti progetti:(i) Un approccio di machine learning multi-omico per prevedere la prognosi dei pazienti con TNBC, integrando dati da diverse omiche …

    catania Repository record

  4. Bayesian model-based clustering of multi-source data

    Coleman, StephenUniversity of Cambridge2022

    … clusters challenging. A demanding problem is analysis of data generated across multiple sources. Bayesian mixture models and their extensions are effective tools for partition inference in this setting as we can use these to describe and infer the relationship between different sources. I …

    cambridge Repository record

  5. TARGETING TYPE-I PRMTS RESTORES PLATINUM SENSITIVITY IN OVARIAN CARCINOMA THROUGH MITOCHONDRIAL METABOLISM

    MONDAL, AYUSIUniversità degli Studi di Milano2025

    … in EOC. We present an integrative multi-omics analysis of carboplatin-resistant A2780 ovarian cancer cells (A2780R) developed via stepwise drug adaptation, revealing pronounced mitochondrial and metabolic rewiring. A2780R cells display an 8.8-fold increase in carboplatin IC50 …

    milano Repository record

  6. Comprehensive Analysis of the Molecular Underpinnings of Pediatric Glioma

    Ryall, Scott Thomas2021

    … we collected tissue from DIPG patients from multiple sites of tumor dissemination and the primary pontine lesion for multi-omics analysis. We uncovered homogeneity of tumor defining alterations, including H3 p.K27M, but heterogeneity of many accessory alterations. Clonal evolution modelling …

    toronto-retro Repository record

  7. Astrocyte and vascular changes contribute to Alzheimer's disease

    Li, JiangtaoVirginia Tech2024

    … AD mouse model: hAPPJ20 mice. First, a multi-omics analysis of cortical astrocyte gene and protein expression was conducted at 3, 6, 12, and 18 months in female J20 and wild-type (WT) mice, revealing significant gene and protein expression differences linked to normal aging and AD …

    vt Repository record

  8. Fusarium poae: Secondary Metabolism and Accessory Chromosomes

    Witte, ThomasUniversité d'Ottawa | University of Ottawa2024

    … In this thesis research, an untargeted metabolomics profiling method was developed and applied alongside population-level, whole-genome sequencing to analyze the chemistry of Canadian F. poae populations. F. poae metabolomes included a mixture of diverse trichothecene mycotoxins and other …

    ottawa-retro Repository record

  9. In vivo and in vitro approaches to characterising axon growth and metabolic alterations in Parkinson’s disease

    Travaglio, MarcoUniversity of Cambridge2022

    … metabolism, using a Drosophila model of PD. Multi-omics analysis of pink1 mutant flies uncovered metabolic and transcriptional modifications in cysteine metabolism which coincided with defects in mitochondrial respiration. These findings confirmed PINK1’s canonical role in mitochondrial …

    cambridge Repository record

  10. Development of knowledge base and methodology for the rational microbiome modulation in irritable bowel syndrome

    Das, AnubhavUniversity College Cork2023

    … of IBS pathophysiology. Firstly, I took a multi-omics analysis approach to investigate alterations in microbiome community composition and structure, predicted functionality, and faecal and urine metabolome, along with dietary habits in IBS. Subsequently, I analyzed the non-bacterial …

    cork Repository record

  11. Discovery of multi-omics biomarkers for toxicity using meta-analysis

    김, 효실2015

    … generation 18 2-1. Gene selection using meta-analysis 18 2-2. Functional analysis of filtered genes by meta-analysis 19 2-3. Gene selection using sPLS-DA approach 19 2-4. Gene selection using wrappers 19 2-5. Generation of a predictive model 20 3. Model and biomarker verification 20 3-1. …

    ajou Repository record

  12. Computational Modeling of Planktonic and Biofilm Metabolism

    Guo, WeihuaVirginia Tech2017

    … of planktonic and/or biofilm cells via multi-omics approaches (e.g., transcriptomics and proteomics analysis). However, these approaches are limited to provide the direct description of intracellular metabolism (e.g., metabolic fluxes) of microorganisms. Therefore, in this study, I have …

    vt Repository record