Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 202 for “"mucus"”.
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Cervical mucus prorperties stratifv risk for preterm birth
… cervix, which is normally protected by a dense mucus plug during pregnancy. This mucus plug, consisting of a tight meshwork of glycoproteins called mucins, should prevent pathogens from accessing the sterile uterine environment. Cervical mucus from women at high risk and low risk for preterm …
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FACTORS AFFECTING THE TRANSPORT OF SOLUTES THROUGH BRONCHIAL MUCUS
The diffusion of solutes in human bronchial mucus gel has been studied. Using the method of layer analysis and radioactive tracers the diffusion coefficients and self diffusion coefficients of several antibiotics and of glucose, sucrose, inulin and decamethonium iodide in mucus have been …
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Pig mucus as an inhibitory agent of HIV-1
… purified mucins sourced from pig and horse mucus, as an alternative and abundant source of material for anti-HIV-1 research. Pig gastric and cervico-vaginal mucus was collected and stirred overnight in 6M guanidine hydrochloride with 10mM Na₂HPO4, 10mM EDTA, 1mM PMSF and 5mM NEM. Gastric and …
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF MUCUS ADHESION PROTEINS OF LACTOBACILLUS REUTERI
Mucus is the first point of contact between the gut microbiota and the host. Mucus adhesins are thought to be key mediators in the mucus adhesion of commensal Lactobacillus species. However, knowledge on the structural or functional basis of adhesin interaction with mucin glycoproteins, the main …
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The biochemical characterisation of respiratory mucus & mucins in normal, asthma & COPD
Airway mucus hyper-secretion is the main cause of mortality and morbidity in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) and is the leading cause of death in South Africa. Mucus is a viscid, slimy visco-elastic gel-like material, which coats the epithelial …
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The role of human breast milk mucus and mucins in HIV-AIDS
Milk molecules such as mucins, antibodies, bactericidal enzymes like lysozymes and fatty acids that lyse bacteria, viral particles and bacterial peptides, offer anti-microbial activity in milk. Despite human breast milk being rich in anti-microbial substances, such as mucin, that protect against …
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Microfluidic enabling technologies for measurement of the selective permeability of the mucus barrier
Mucus is a biological hydrogel which lines the wet (non-keratinized) epithelia of the body. Mucus provides a gateway between the cells of the epithelium and the outside world, and is postulated to provide a selective filtering function which is critical to physiological functioning and has been …
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The Role of Mucus in the Ultraviolet Radiation Protection of <em>Porites astreoides</em>
… tissues, MAAs have also been extracted from mucus present on colony surfaces. Many functions, including protection from sedimentation, salinity fluctuations, and temperature changes, have been attributed to coral mucus. The presence of MAAs within mucus suggests an additional function: …
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Mechanism and role of calcium in excitation-mucus secretion coupling in human colonic epithelium
Defective mucus barrier function is one of the contributing factors for inflammatory bowel disease (IBD) pathogenesis. Understanding the regulation of mucus secretion is essential for developing new therapies. Cholinergic signals have been shown to stimulate mucus secretion, but the mechanism is …
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The role of mucus in the cross talk between gut bacteria and the host
… in a dynamic interaction with the immune system. Mucus is the first point of contact of the microbiota with the host, acting as a first line of defence. Furthermore γδ intraepithelial lymphocytes (IELs) respond to the invading bacteria that circumvent the mucus barrier. In this study two …
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Investigating the molecular mechanisms of the interactions between Lactobacillus reuteri strains and intestinal mucus
Mucus is the first point of contact between the gut microbiota and the host. Here we used the gut symbiont Lactobacillus reuteri to investigate the molecular mechanisms underlying the interactions between gut bacteria and mucus. Firstly, the mucus binding ability of a collection of L. reuteri …
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Physical and chemical changes in porcine gastric mucus in the normal and ulcerated status
… the investigation of the biochemical aspects of mucus secretion in both the normal state and at various states of ulceration. The main findings are summarised below: Mucus scrapings of the cardiac gland region of the pig stomach had a higher water and total protein content in the pre-ulcerated, …
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A low Reynolds number flow problem with application to spermatozoan transport in cervical mucus.
Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Thesis. 1972. M.S.
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The biochemical analysis of mucus and mucins in respiratory diseases with a focus on tuberculosis
… The respiratory tract is lined by a layer of mucus which protects the airways and lungs against injury by foreign agents. The main constituents of this layer of mucus are mucins. MUC5AC and MUC5B are the predominant respiratory tract mucins. However, little is known of the association between …
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Investigation of two-component signaling systems in Pseudomonas aeruginosa and their roles in the mucus barrier
All living things must be able to sense and respond to signals in their environment in order to grow and survive. For bacteria, a common means through which this occurs is via two-component signaling systems, which are typically comprised of a membrane-bound histidine kinase that senses external …
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Pathogenic roles of Pseudomonas aeruginosa-derived volatile organic compounds in airway mucus hypersecretion: Molecular mechanisms and immune modulation
This Dissertation was approved for publication on 2024-12-04 at 14:52.
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A microfluidic mucosal airway model to study airway mucosal function and pathogenesis
Airway mucus hypersecretion or impaired clearance is one of the key pathophysiological features of airborne infection, allergy and severe respiratory diseases. As foreign particles enter the lungs, the airway becomes inflamed and excessive amount of mucus is generated in response. However, little …
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Investigating proteomic profiles of skin mucus and blood plasma of rainbow trout (Oncorhynchus mykiss) exposed to low concentrations of waterborne nickel
… we examined changes in protein profiles of skin mucus and blood plasma of rainbow trout using untargeted proteomics. The use of non-lethal blood sampling and non-invasive mucus sampling is becoming increasingly desirable to study toxicological effects. Findings suggest that the proteome of …
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