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Showing 1 to 2 of 2 for “"mtIF2"”.
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The Effect of Leucine Supplementation on Biomarkers of Mitochondrial Biogenesis and Protein Synthesis in Soleus Muscle of Rats Fed a High-Fat Diet
… of mitochondrial protein synthesis markers TFAM, mtIF2, and TUFM, and mitochondrial biogenesis regulatory factors PGC-1α and COX-IV. METHODS: Male, Sprague-Dawley rats (n = 30 / dietary treatment) were fed either a control diet (C), control + leucine (CL), high-fat (HF), or high-fat + leucine …
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Mitochondrial mRNA Translation is Required for Maintenance of Oxidative Capacity
… mRNA translation initiation factor (mtIF2) is necessary to maintain oxidative capacity in cardiomyocytes. Methods Using a combination of animal and cell culture experiments, we first analyzed the oxidative detriments of the myocardium using an LLC tumor implantation model and followed …