Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"mouse blastocysts"”.
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Self-Renewal Requirements of Human Embryonic Stem Cells and Their Engraftment Potential in Mouse Blastocysts
… Embryonic stem cells were first derived from mouse embryos (mESCs), and years of work have demonstrated their utility to developmental research, but relatively little is known about human ESCs. The experiments described below address two fundamental questions in hESC biology: First, what are …
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Lack of Inflammatory Response in Mouse Embryonic Cells to Listeria Infection
… research has shown that key cell types within mouse blastocysts, including embryonic stem cells (ESCs) and trophoblast stem cells (TSCs), exhibit remarkable resilience against the cytotoxic effects associated with viral infections and embryotoxic cytokines, such as TNFα and IFNγ, both of which …
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In vivo analysis of homing pattern and differentiation potential of cells deriving from embryonic and adult haematopoietic regions
… established cell lines injected into murine blastocysts find their way back home and seed preferentially at the site of their origin. Furthermore, can they change their fate and differentiate to unrelated cell types when exposed to the embryonic environment. This survey was based on the fact …
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Patterns of embryonic mortality in mice after exposure to 137cs gamma irradiation
… effects of ¹³⁷cs irradiation on the viability of mouse embryos irradiated in vitro and subsequently transferred to recipient females or cultured in vitro. The first experiment was designed to evaluate the viability of embryos after combinations of whole body irradiation to the recipient (0, 100 …
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Role of Histone Lysine Demethylase, KDM1B, in Trophoblast Stem Cell Self-Renewal and Differentiation
… stem cells (TSCs) can be derived from the TE of mouse blastocysts. TSCs have proven an invaluable research tool to study processes of early placentation in vitro. Despite the placenta’s central role in reproduction, our understanding of the regulatory networks that orchestrate TSC self-renewal …