Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"motoneuron differentiation"”.
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Molecular and cellular regulation of motoneuron differentiation of human neural stem cells
… into choline acetyltransferase (ChAT) motoneurons in vitro and after transplantation into the rodent spinal cord in vivo. However, the mechanisms surrounding FHL-induced motoneuron differentiation of hNSCs are unknown. Thus, the overall goal for this thesis was to further understand the …
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VOLTAGE GATED SODIUM CHANNEL AND NEURONAL DIFFERENTIATION. IMPLICATIONS IN AMYOTROPHIC LATERAL SCLEROSIS PATHOGENESIS
… together with morphological alterations of motoneuronal phenotype. In this scenario, we decided to deeper investigate the role of VGSCs in neurite elongation, by taking advantage of the NSC34 cell line, an in vitro model often used in the study of motoneuron disease. Thus, we used two …
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A Developmental Pathway for Epithelial-to-Motoneuron Transformation in C. Elegans
… Notch/Delta signaling is implicated in the differentiation of these cells into motoneurons through control of their proliferative state. Down-regulation of the Notch-dependent Hes1 and Hes5 transcriptional inhibitors in differentiating cells induces expression of the proneural bHLH …