Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 925 for “"motility"”.
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Factors governing gastrointestinal motility
… role of changes in gastrointestinal (GI) motility and GI hormones as well as the possible significance of alterations in energy expenditure that occur as a consequence of weight loss.Methodology: My preliminary studies involved a systematic review of GI motility in obesity, and …
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cell motility and machine learning
Cell migration is a necessary function in organisms. It is relevant to wound healing, immune reaction, cancer expansion. One example is durotaxis: Cells exhibit qualitatively different behaviors on substrates with different rigidities. The fact that cells are more polarized on the stiffer substrate …
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Molecular Drivers of Bladder Cancer Motility
… to distant sites. The study of BC cell motility will both enable development of anti-invasion therapeutics to limit progression of early-stage disease and improve our understanding of the metastatic process which drives patient mortality in BC. BCs display a great deal of intertumoral …
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The development of motility in spermatozoa
Mammalian spermatozoa acquire the capacity for motility during passage through the epididymis. This study on rat spermatozoa shows that pH, cAMP and protein kinase C (PKC) all play an important role in the initiation of motility. pH has the most critical role and until the initial pH change in …
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Novel Modulators of Human Sperm Motility
… by asthenozoospermia (reduced sperm motility). Incredibly, there is currently no known treatment for this condition, and the only option is Artificial Reproduction Technology (ART) which is expensive and invasive. The development of a novel treatment would fulfil a therapeutic niche …
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Motility and Chemotaxis of Erwinia Amylovora
Environmental and cultural factors influence the motility of Erwinia amylovora by affecting either flagella synthesis of motility itself. Flagella synthesis is temperature dependent with an optimum at 18-23(DEGREES)C. However, bacterial cells grown at these temperatures are actively motile even at …
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Physical minimal models of amoeboid cell motility
… to investigate single and collective cell motility in three different settings. The key question we strive to answer is whether cell locomotion is a physical process that can function without the biochemistry that controls it. First, we examine contact inhibition of locomotion (CIL), which …
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Motility of Swimming Bacteria Hydrodynamics and Statistics
… trajectories, since it allows to quantify motility in terms of statistical measures, such as diffusivity and drift velocity, which can be measured experimentally. After a general discussion of the model, we demonstrate its use by applying it to the dynamics of bacteria-driven microswimmers, …
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In vitro reconstitution of Central Spindle Motility
… a myriad of cellular processes including cell motility, polarisation and mitosis. Positioning is actively controlled by organelle specific attachment, often involving dedicated motor proteins, to cytoskeletal network. While much is known about the biophysics of motors on isolated tracks, how …
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Symmetry-breaking motility and RNA secondary structures
… work on three separate topics: the spontaneous motility of functionalized particles, the designability of RNA secondary structures, and the statistical mechanics of homopolymer RNAs. For the work on spontaneous motility, we were motivated by in vitro experiments investigating the …
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Genetics and physiology of motility by Photorhabdus spp
… or symbiotic bacteria utilize various methods of motility to reach favorable conditions, colonize a host, or have motility genes that also regulate virulence expression. It is not known how motility is regulated, or how it may confer an advantage, in the complex life cycle of …
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Molecular Mechanism of Tetraspanin CD9 Mediated Cell Motility
… and LY294002 inhibited CD9 promoted cell motility in Chinese hamster ovary (CHO) cells. In contrast, inhibitors targeting protein kinase C or mitogen-activated protein kinase had no effect on CD9 driven CHO cell motility. Furthermore, inhibition of PI-3K activity in CHO cells by …
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Compounds Modulating Calcium and Motility in Human Spermatozoa
… of drugs to target asthenozoospemic (low sperm motility) males is a valuable area of research, with clinical potential to improve the take home baby rate.<br/><br/>Previous work using a Flex Station HTS assay and calcium as a surrogate for motility, identified 10 hit compounds from the UoD DDU …
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Synthetic Peptide Ligand Mimetics and Tumor Cell Motility
Human tumor cell progression and metastasis is partially dependent on the ability of tumor cells to adhere to the proteins of the extracellular matrix and migrate to distant locations. Using a combinatorial screening approach, six novel D-amino acid containing peptides were identified and analyzed …
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Gastro-duodenal motility & nutrition in the critically ill.
… options. The abnormalities in gastrointestinal motility underlying delayed GE in the critically ill are poorly characterised. Simultaneous manometric and gastric emptying measurements were performed in 15 mechanically ventilated patients and 10 healthy subjects. These studies demonstrated that …
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Motility and Chemotaxis of Pseudomonas Syringae Subsp. Glycinea
Flagellar motility in Pseudomonas syringae subsp. glycinea (Psg), as determined by capillary assay, is best at sub-optimal growth temperatures (17-27 C) and inhibited at higher temperatures. Motility is optimal in the presence of 10$\sp{-5}$ M EDTA in potassium phosphate buffer at pH 6-7. Reduced …
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Structure, function, and dynamics of cell motility proteins
… structure and function relationships in cell motility proteins at atomic resolution. (1) To analyze motions in cell motility proteins an algorithm is described to identify and visualize the movements of rigid domains about common hinges in proteins. In comparing two structures, the method …
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Molecular characterization of motility genes in Bacillus subtilis
The synthesis of the bacterial flagellum is a complex process requiring up to fifty gene products in organisms such as Escherichia coli and Bacillus subtilis. Several genes involved in the process of flagellar synthesis have been identified and characterized from the che/fla operon of B. subtilis, …
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Effects of hyperlipidemia on gallbladder motility in dogs
… that hyperlipidemia could impair gallbladder motility and contribute to gallbladder mucocele formation. Objectives: The objective of this study was to compare gallbladder motility in dogs with hyperlipidemia to healthy, control dogs using ultrasonography. We hypothesized that hyperlipidemic …
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