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Showing 1 to 20 of 69 for “"monosaccharide"”.
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Darstellung langkettiger Monosaccharide mittels Olefin-Metathese-Reaktion
… sich das Augenmerk zunehmend auch auf höhere Monosaccharide. Im Rahmen dieser Dissertation wurde ein neuer Zugang zu diesen langkettigen Monosacchariden vorgestellt. Dabei werden als Edukte diverse Allylalkohole verwendet, die sich jeweils auf Basis von D-Mannose, D-Glucose, D-Galactose oder …
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Electronic and solvent effects on monosaccharide conformations
… group rotational preferences of the monosaccharides glucose and galactose are different from each other and non-intuitive (from a steric point of view) in their preferences for gauche conformers. These molecules exhibit very different biological and thermodynamic properties in, for …
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Electronic and solvent effects on monosaccharide conformations
… group rotational preferences of the monosaccharides glucose and galactose are different from each other and non-intuitive (from a steric point of view) in their preferences for gauche conformers. These molecules exhibit very different biological and thermodynamic properties in, for …
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Synthesis and Characterization of Monosaccharide-derived Low Molecular Weight Gelators
<p>Low molecular weight gelators (LMWGs) are interesting materials whose applications are as diverse and wide ranging as their molecular structures. These materials self-assemble through the formation of non-covelent intermolecular forces and interactions to form supramolecular assemblies that trap …
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Mechanisms underlying monosaccharide stimulated incretin hormone secretion from the intestine
… sub types L-cells and K-cells respectively. The monosaccharide glucose is a trigger for incretin secretion, which requires glucose uptake via the sodium-dependent glucose transporter 1 (SGLT1) expressed by L-cells and K-cells, as demonstrated by *in vitro* cell based studies. SGLT1 is expressed …
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The amino acid and monosaccharide content of the cell walls of Thiobacillus thiooxidans
"The objectives of this investigation were: (a) to culture large quantities of Thiobacillus thiooxidans cells, (b) to find an acceptable method of rupturing the cells, (c) to find an acceptable method of isolating the cell walls, and (d) to analyze the cell wall components, especially the amino …
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The influence of monosaccharide types (D-glucose, D-mannose and D- galactose) in inducing lactic acidosis in goats
Call number: LD2668 .T4 1978 M78
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Antimicrobial Carbohydrate Vaccines: Development of Burkholderia pseudomallei immunogens
… infection based on both bottom-up synthetic monosaccharide constructs and top-down CPS-1 conjugates. Initially this thesis focused on the development of a monosaccharide antigen based on the 6-deoxy-D-manno-heptose building block of CPS-1. The antigens were conjugated to TetHc carrier protein …
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Enzyme Kinetics of Recombinant Human Arylsulfatase B (rhASB)
… problem of substrate limitation. Using a direct monosaccharide hydrolysis assay in conjunction with the same natural substrate bioassay, this project will attempt to provide insight to the kcat, the turnover number, or number of reactions an enzyme can process, Km, the substrate concentration at …
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Structural analysis of glycolipid-derived oligosaccharides from metabolically radiolabelled colorectal carcinoma SW1116 cells
… labelling the cells with radioactive monosaccharide precursors. SW1116 cells (1 x 10⁶) metabolically labelled with 222 μCi/ml of either 6-[³H]-D-galactose (25 Ci/mMol) or 6-[³H]-D-glucosamine (38 Ci/mMol) for 30 hours, incorporated 1%-3% of the radioactivity into their glycoconjugates. …
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An NMR and molecular modelling study on the solution conformation of Heparan Sulphate: new insights into the relationship between structure and function
… groups. Consistent with previous studies, at the monosaccharide level, sulphation was found to influence iduronate conformational behaviour. However, with the data presented, a number of gaps in the literature have now been filled, and it is now possible for the first time to predict the balance …
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Site-selective C-H Bond Diversification of Glycosides
… selective and efficient catalytic system for monosaccharide functionalization: 1) site-selective halogenation & derivatization of sugars, 2) expedient synthesis of L-glucose and 3) diastereoselective C-H alkylation of sugars. These radical-based transformations harness polarity compatibility …
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Production and characterisation of yeast cell wall preparations with binding activity against Salmonella and Escherichia coli.
… and increase its MOS content. The cell wall monosaccharide content (e.g. glucose and mannose) of a number of samples was significantly altered depending on the sole carbon source in the growth medium. However, the effect of carbon source on the cell wall monosaccharide content was strain …
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Automated synthesis of the Lewis blood group oligosaccharides
… marker Le[superscript]y-Le[superscript]x monosaccharide building blocks was achieved in just 23 hours, while the syntheses of the tumor markers Lewis X, a pentasaccharide, and Lewis Y, a hexasaccharide, required only 12 and 14 hours respectively. The automation of carbohydrate synthesis …
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Design, Synthesis and Characterization of D-glucosamine Low Molecular Weight Gelators
… materials. We have previously showed that monosaccharide derivatives can form effective low molecular weight gelators for both organic solvents and aqueous mixtures. In this research, we have studied the gelation capability of several glucosamine derivatives. Several series of 4,6-O-acetal …
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Synthesis and Properties of Selectively Modifiable Cyclodextrin Analogues
… 38 +/- 10 M-1. In addition, the synthesis of a monosaccharide cyclotrimer and a disaccharide cyclodimer is presented that were demonstrated to complex 2,4-hexadiyne-1,6-diol with association constants of 8.8 +/- 1.5 M -1 and 10.4 +/- 1.1 M-1, respectively. Alternate synthetic routes which …
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Structural analysis of capsular polysaccharides produced by some emerging Klebsiella pneumoniae serotypes
… NMR experiments can be used to determine the monosaccharide composition, anomeric configurations ( or ), linkage positions and sequence of residues in the polysaccharide RU. NMR can also identify the presence and positions of non-carbohydrate substituents including O-acetyl and pyruvate …
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The Characterization of Glycosaminoglycans and Metallic Dianions in the Gas Phase
Singly, doubly and triply deprotonated monosaccharide and disaccharide molecules of the Heparin family of Glycosaminoglycans (GAGs) have been studied in the gas phase to investigate their geometric structures and intrinsic stabilities. Low energy Collision Induced Dissociation (CID) in a quadrupole …
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Synthesis of Polysaccharide Aldehydes or Ketones and Fabrication of Derived Hydrogels or Microgels
… to prepare polysaccharide aldehydes by attaching monosaccharides to polysaccharide chains. Herein, we describe the approach of attachment through amination between amine group at the C2 position of the monosaccharide and carboxylic acid groups on polysaccharides. In this way, more reducing ends …
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