Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"monocyte chemoattractant protein 1"”.
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Platelet micro-particles induce angiogenesis through the delivery of the micro-RNA Let-7a into endothelial cells
… (integrin beta-1 and integrin associated protein) and downstream caspase-3 activation were explored by Let-7a inhibition prior to PMP treatment. MicroRNA dependent modulation of proangiogenic proteins including monocyte chemoattractant protein-1 and placental growth factor, and recruitment …
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Association Between Fluoride Exposure and Immune System Biomarkers in Pregnancy
… IL-8, tumor necrosis factor-alpha (TNF-α), monocyte chemoattractant protein-1 (MCP-1), and C- reactive protein (CRP) from plasma samples collected during the third trimester of pregnancy. Results: We observed a departure from linearity in the association between WFC and CRP, such that CRP …
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Sphingosine-1-phosphate in mast cell-mediated allergic responses
… S1P stimulated secretion of the chemokine, monocyte chemoattractant protein 1 (MCP-1/CCL2), from these macrophage-depleted and purified CB-MCs.
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Acrolein as a novel therapeutic target for spinal cord injury induced neuropathic pain
… we have observed a significant increase of monocyte chemoattractant protein-1 (MCP1), a pro-inflammatory chemokine that is also known be increased upon acrolein stimulation and capable of sensitizing TRPA1 following SCI. Similarly, we observed a heightened excitatory response of DRG sensory …
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Protease Activation and Inflammation in Acute Pancreatitis
… activation (aCAP, CAPAP) and inflammation (Monocyte Chemoattractant protein-1 (MCP-1) and CRP) were found to be elevated within 24 hours in patients with severe AP. Protease activation decreased after 48 hours, yet inflammation persisted for a longer period of time. Markers of pancreatic …
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Polyunsaturated fatty acids and immune cell functions
… resulted in significantly decreased ex vivo monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1a (MIP-1a) and interleukin-8 (IL-8) production from PHA-or LPS-stimulated PBMC compared with baseline. It also significantly decreased cell surface expression of CD36+, …
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Anti-Inflammatory Mechanism By Oxysterols In Cultured Rat Brain Astrocytes
… and tumor necrosis factor transcripts, and monocyte chemoattractant protein-1 release. Oxysterols are known as nuclear receptor liver X receptor agonists, and these inhibitory effects were observed with synthetic agonists of liver X receptor and retinoid X receptor in a similar manner. In …
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Aging Delays and Exercise Accelerates Wound Healing and Decreases Inflammation in Old Mice
… (IL-1beta), interleukin-6 (IL-6), keratinocyte chemoattractant (KC), monocyte chemoattractant protein-1 (MCP-1), and tumor necrosis factor alpha (TNF-alpha). No significant differences in wound size were found as a result of exercise in young mice. However, exercise significantly decreased wound …
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Using urinary MCP-1 and TWEAK to assess disease activity in a cohort of South African patients with lupus nephritis
… a need for noninvasive and accurate biomarkers. Monocyte chemoattractant protein-1 (MCP-1) and tumour necrosis factor-like weak inducer of apoptosis (TWEAK) have been implicated in the pathogenesis of LN and are thus potential biomarkers for disease activity monitoring. Methods: In this study …
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Correlation of urinary mcp-1 and tweak with renal histology and early response to therapy in newly biopsied patients with lupus nephritis in cape town, South Africa
… most centres. Novel urinary biomarkers such as monocyte chemoattractant protein-1 (MCP-1) and tumour necrosis factor-like weak inducer of apoptosis (TWEAK) are secreted in the kidney and may be useful for predicting histological class, monitoring flares and assessing response to therapy. We …
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Periventricular white matter damage in the post-natal brain in hypoxic conditions
… factor-a (TNF-a), interleukin-1ß (IL-1ß), monocyte chemoattractant protein-1 (MCP-1), chemokine (C-C motif) receptor 2 (CCR2), and macrophage-colony stimulating factor (M-CSF) expression was observed. Immunoexpression of these was specifically located in AMC from 24h-7d. However, CSF-1 …
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INITIATION OF EXPERIMENTAL ACUTE PANCREATITIS AND MODULATION OF INFLAMMATORY RESPONSE
… predominantly causes early expression of CCL2 [monocyte chemoattractant protein-1 (MCP-1)] and subsequent early influx of monocytes. Increased expression of CXCL [cytokine-induced neutrophil chemoattractant-1 (CINC-1)] was not seen and neutrophils were shown to appear in the tissue later during …
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Roles of the P2X7 receptor in C6 astroglioma: in vitro and in vivo studies
… were found to express the P2X7R at both mRNA and protein levels. The P2X7Ragonist, 2', 3 '-(benzoy1-4-benzoy1)-ATP (BzATP) induced an increase in intracellularCa2+ concentration, an effect which was largely inhibited by periodate-oxidized ATP(OxATP), an irreversible P2X7R antagonist. BzATP …
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Peptide hydrogels as novel scaffolds for dental pulp cell culture
… normal T cell expressed and secreted (RANTES), monocyte chemoattractant protein-1 (MCP-1) and vascular endothelial growth factor (VEGF), relative to culture in 10% RGD Biogelx hydrogel however, neither type of hydrogel was found to be favourable for osteogenic differentiation. <br/><br/>The …
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Role of 5-Lipoxygenase in Interleukin-4-Induced Oxidative Stress and Inflammation in Vascular Endothelium
… as vascular cell adhesion moledule-1 (VCAM-1), monocyte chemoattractant protein-1 (MCP-1), and interleukin-6 (IL-6) in vascular endothelium. 5-Lipoxygenase (5-LOX) is one of the key sources that generate reactive oxygen species (ROS) via metabolic pathways of arachidonic acid. Although 5-LOX has …
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High Fat Diet Effects on Erythrophagocytosis and MCP-1 Levels in Mice
… subsequent inflammation. Immune cells, such as monocytes, respond to chemokines and differentiate into macrophages, engulfing oxidized lipids, and forming foam cells within the vessel wall. Red blood cells (RBC) are known to bind chemokines through the Duffy antigen receptor for chemokines …
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Statin-Mediated Attenuation of Chemokine Expression in Peripheral Nerve Vascular Endothelial Cells
… of GBS. Literature indicates that TNF-α, monocyte chemoattractant protein-1 (MCP-1), and intercellular adhesion molecule-1 (ICAM-1) are locally increased in patients with GBS, correlating with disease severity. Similar findings have been demonstrated in an animal model of GBS, experimental …
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Effekte von Leptin- und MCP-1-Applikation auf funktionelle Parameter der Arteriogenese : eine experimentelle Studie mittels Ultraschallflussmessungen, Mikrosphärperfusion und Proliferationsanalyse
… Ein bekanntes arteriogenes Zytokin, MCP-1 (monocyte chemoattractant protein-1) wurde mit dem Adipozytokin Leptin, das bisher nicht hinsichtlich seiner Wirkung auf das Kollateralarterienwachstum <br>untersucht war, verglichen. Zur Validierung des Gefäßwachstums wurden <br>Proliferationsmarker …
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The bioactive role of omega-3 endocannabinoid epoxide regioisomers
… (iNOS), tumour necrosis factor α (TNF-α) and monocyte chemoattractant protein-1 (MCP-1) as well as increasing anti-inflammatory mRNA levels of arginase-1 (Arg-1) in LPS stimulated BV-2 microglia. Collectively, we showed that omega-3 eCB epoxide regioisomers differentially activate cannabinoid …
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Die Rolle des Tumorsuppressors p53 für die TNF-alpha-vermittelte Induktion des MCP-1-Gens
… spezifischer Gruppen von Leukozyten. Das "Monocyte-Chemoattractant-Protein-1" (MCP-1/CCL2) ist ein wichtiges Mitglied der Chemokin-Familie und löst die Infiltration von Monozyten/Makrophagen aus. Die Expression von MCP-1 tritt bei verschiedenen Krankheiten, die durch den Einstrom von …
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