Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"molecular therapy"”.
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Molecular therapy for mucopolysaccharidosis Type I
… vectors as a supplement to enzyme replacement therapy and HSCT for the treatment of Hurler syndrome.
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OTULIN's Novel Regulatory Mechanisms in Genotoxic and Inflammatory NF-kB Signaling
… is aggressive but cannot be treated with hormone therapy or molecular therapy due to the lack of a target. Chemotherapy is a systemic treatment that works by attacking rapidly growing cells, which is initially more effective for TNBC patients than those individuals with the hormone …
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The development and characterisation of MicroRNA and gemcitabine nanotherapies for the treatment of pancreatic cancer
… significant role of cellular variation and <br/>molecular signature on the effectiveness of miR-143/145 as a therapeutic option. <br/><br/>In contrast, administering gemcitabine triphosphate via the developed nanoparticles resulted in consistent efficacy among the cell lines suggesting a common …
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Durability and Longevity of Gene Edited DMD Skeletal Muscle
The content of this work is adapted with or without modifications from the previously published articles that are cited below. Sections that have been reproduced from previously published work have been clearly indicated at the beginning of each section.
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EMISSIVE PEPTIDE NUCLEIC ACIDS (PNAS): POTENTIAL TOOLS FOR INNOVATIVE DIAGNOSTICS AND THERAPEUTICS
… new and attractive tools for diagnostics and therapy. To this purpose, this thesis focused on exploring and validating synthetic methodologies for the creation of modified PNAs. The work of the thesis was divided into four main research activities, with the common feature of creating emissive …