Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"molecular subtyping"”.
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MOLECULAR SUBTYPING OF STAPHYLOCOCCUS AUREUS ISOLATES FROM THE U.P. COMMUNITY FOR THE PRESENCE OF TOXIN-ENCODING GENES
… aureus </em>infection is suspected. PCR-based subtyping was utilized to test for the presence of fifteen toxin genes: <em>lukAB, lukED, pvl, hlgA, hlgC, tst, eta, hla, hlb, hld, sea, seb, sec, sed, </em>and <em>see.</em> Isolates were also tested for the presence of the <em>mecA</em> gene, …
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Identification of targetable mediators of resistance to chemotherapy in oesophageal adenocarcinoma
… are low and survival is poor. Increased molecular understanding of this heterogeneous disease is needed to overcome resistance to chemotherapy and develop novel therapeutic strategies. This study uses gene expression data to perform unbiased molecular subtyping followed by functional …
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Fast But Right: Outbreak Surveillance And Foodborne Knowledge Infrastructure
… current early-warning, real-time system based on molecular subtyping. Through these analyses, I demonstrate how these systems made outbreaks visible not only from a technical perspective, but also from social, political, and economic perspectives as well.
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The Use of Texture Analysis in Breast Magnetic Resonance Imaging
… subtype and grading, as well as state-of-the-art molecular subtyping. While larger patient data sets are required to demonstrate this definitively, initial results show encouraging findings.<br/><br/>It has also been shown that TA can be used in patients undergoing NAC to indicate whether the …
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The role of tissue inflammation in Kenyan women with breast cancer
… The immune landscape of breast cancer (BC) molecular subtypes from Sub Saharan Africa is understudied and findings are mainly extrapolated from studies in Caucasians. The objective of this study was to describe the cellular and signalling milieu of BC tumour microenvironment and its …
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Epigenetic dysregulation of novel candidate genes in melanoma
… lead to the generation of new strategies for molecular subtyping, discovery of diagnostic and prognostic biomarkers and development of novel therapeutic targets. <br/><br/>In the present study, I have identified a panel of promising epigenetic melanoma biomarkers by exploiting both a …
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Establishing the feasibility of using ctDNA for molecular profiling in DLBCL
DLBCL is a molecularly heterogeneous disease. Many clinical trials have failed to demonstrate improvements to survival by altering first line therapy. This may be due to failure to stratify patients in a way that reflects this molecular heterogeneity. Over the last 5 years, three large DLBCL …
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Longitudinal study of Salmonella enterica, Escherichia coli O157:H7, and Listeria monocytogenes in a small and very small fresh meat processing plant environment
… of the recovered pathogen isolates by molecular subtyping (e.g. PFGE, ribotyping) was performed to gain insight in contamination transmission within the facilities. S. enterica was isolated from 15 (4.5%) and 8 (2.4%) samples from Plant 1 and Plant 2, respectively. Characterization by …