Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"molecular investigation"”.
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Molecular investigation of the wood/pMDI adhesive bondline
… This research describes efforts to learn more molecular information about the pMDI-wood bondline, and to further improve the bonding performance. In order to correlate molecular phenomena with macroscopic performance of wood-adhesive bondline, low frequency molecular motions in wood were probed …
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Exploring Pain Neurobiology: Molecular Investigation of Genetic Sensory Disorders
… Pain (CIP) arises when genetic mutations disrupt molecular components that are essential to the development or postnatal function of this system. Understanding how these mutations alter the encoded protein, and subsequently impact sensory neuron signalling, can reveal new strategies to modulate …
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The molecular investigation of Stargardt disease in South Africa
Hereditary macular degeneration describes a group of conditions causing macular pathology. Stargardt disease (STGD) is the most common inherited juvenile macular dystrophy characterised by severed reduction of central visual acuity and normal peripheral vision. The ABCA4 (adenosine triphosphate …
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DNA mechanical nanoresonator as a tool for structural molecular investigation
L'abstract è presente nell'allegato / the abstract is in the attachment
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Molecular investigation of bovine leukemia virus in selected wildlife in Zambia.
Bovine Leukemia Virus (BLV) is a member of the genus Deltaretroviruses of the family Retroviridae and causes Enzootic Bovine Leukosis (EBL). The most common manifestation of EBL is persistent lymphocytosis, which is characterized by lymphocyte count above 7500/µL of blood, with about 5-10% of cases …
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Molecular investigation of bovine leukemia virus in selected wildlife in Zambia.
Bovine Leukemia Virus (BLV) is a member of the genus Deltaretroviruses of the family Retroviridae and causes Enzootic Bovine Leukosis (EBL). The most common manifestation of EBL is persistent lymphocytosis, which is characterized by lymphocyte count above 7500/µL of blood, with about 5-10% of cases …
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Molecular investigation if the rat jejunal active nucleoside transport protein rCNT1
… study involved a bi-directional approach to the investigation of this protein by the analysis of its distribution in rat tissues at both the cellular and subcellular levels, in addition to structural investigation of rCNT1 by protein chemistry and gene manipulation techniques. A model originally …
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Molecular investigation of competence development by streptococcus pneumoniae during in vivo infection
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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The cellular and molecular investigation of Wnt/FZD signalling during spinal cord neurogenesis
Spinal cord development has been studied extensively and is a model for embryonic patterning and cell differentiation. These processes are governed by extracellular and intracellular signaling and require gene transcription. Wnt signaling has been shown to be involved in dorsal-ventral patterning …
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A clinical and molecular investigation of two families with Simpson-Golabi-Behmel syndrome
Includes abstract (p. 30-32). Includes bibliographical references.
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Towards the full molecular investigation of protein kinase a mediated catalysis by NMR spectroscopy.
… hereditary disease, dilated cardiomyopathy. The molecular basis of disease in this situation could result from irregularities in the association of these PLN mutants with PKA. The work presented here lays the foundation for obtaining the molecular details which govern these interactions to …
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Molecular investigation of the trinucleotide repeats within the Huntington disease gene in Southern Africa
… to amplify each trinucleotide repeat separately. Molecular investigations of 3 Southern African (SA) populations (SA indigenous black population, Mixed ancestry, and Caucasian populations) revealed that the (CAG)n repeat on the 300 non-HD associated chromosomes ranged from 11-37 repeats while …
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A molecular investigation of the antimicrobial functions of the human S100 host-defense proteins
… its Zn(ll)-sequestration capacity through intramolecular disulfide-bond redox chemistry, and that Ca(II) ions exert an indirect modulatory effect on the Zn(Il)-binding properties of this protein. In the second half of this thesis, we examine the bactericidal properties of the four S100 proteins. …
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Post-mortem Molecular Investigation: exploring genetic variation in CYP2D6 in deceased individuals at Salt River Mortuary
… drug intoxication are referred for medico-legal investigation, in order for cause of death to be determined. Sometimes, it remains ambiguous as to whether the drug intoxication was suicidal or accidental, even after a full post-mortem examination. Literature has shown that molecular analysis of …
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A molecular investigation of Huntington disease; origins of the mutation and current prevalence in South Africa
… at less than 0.01 per 100 000 individuals. Molecular genetic analyses have since revealed links between the white and coloured subpopulations which would explain the similarity in prevalence; however, our knowledge of the genetics of HD in the black subpopulation, has been sorely lacking. …
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A molecular investigation of the novel gene underlying autosomal dominant retinitis pigmentosa in a South African family
… epithelium function. Over the last decade, investigations into the patho-physiology of RP have identified numerous disease-causing genes and loci (for a current listing refer to the web site http://www.sph.uth.tmc.edu/Retnet/). A study of a South African family with an autosomal dominant …
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Molecular investigation of the influence of environmental factors and subinhibitory antibiotic concentrations on the biofilm formation in Staphylococcus epidermidis
… S. epidermidis strains. This work aimed on the investigation of external factors regulating the ica expression in S. epidermidis. For this purpose, a reporter gene fusion between the ica promoter and the beta-galactosidase gene lacZ from E. coli was constructed and integrated into the chromosome …
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Epidemiological Features of Central Nervous System (CNS) Infections in Taiwan and Molecular Investigation of CNS Infections of Unknown Cause
… or encephalitis of unknown cause using molecular methods. In the second chapter, I review the literature on the epidemiology of meningitis and encephalitis, and current diagnostic approaches, focusing on the strengths and limitations of various diagnostic methods. In the third chapter, I …
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