Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"molecular immunology"”.
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Regulation of The Expression and Lysine Acetylation of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (LPCAT2) in RAW264.7 Cells
… This research aims to understand further the molecular mechanisms of the enzyme – LPCAT2, that leads to its involvement in regulating macrophage inflammatory responses. Building on pre-existing work on the role of LPCAT2 in inflammation, the primary research question is – “How Does LPCAT2 …
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Selective allodepletion to improve anti-viral and anti-leukaemic responses after haploidentical transplantation
Immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical SCT, but infection and leukaemic relapse remain problematic. To develop a rational approach to refining allodepletion, we characterized the expression of surface markers and cytokines on proliferating …
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Molecular basis of TAPBPR-mediated peptide editing on MHC class I molecules
… peptide editing. I further addressed the molecular basis governing the compatibility between TAPBPR and MHC class I molecules, by screening a wide panel of human leukocyte antigen (HLA) class I allotypes for their relative propensities to undergo peptide editing by TAPBPR. TAPBPR displayed …