Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"molecular farming"”.
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Yeast and plant cells as biofactories for recombinant proteins : evaluation of novel expression and downstream processing strategies
… (IMAC), expanded bed adsorption (EBA) and biomolecular interaction analysis (BIA) – for recombinant protein production in yeast and tobacco was evaluated. These technologies were successfully combined into strategies for the efficient isolation of three His6-tagged recombinant proteins …
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Comparative study of the subcellular localisation and the N-glycosylation patterns of a recombinant glycoprotein expressed in Oryza sativa, Nicotina tabacum and Medicago truncatula
… for the production of pharmaceutical proteins by molecular farming.
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RNA regulatory elements and translational control
… regulatory system with potential application in molecular farming. The project has described a number of translational features and genetic elements involved in translational regulation, contributing towards our understanding of the physiology and virulence of the examined pathogens, and provides …
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Enhancement of plant expression vectors using replication and silencing suppressor elements
Molecular farming is gaining traction as a cost-effective platform to produce recombinant proteins. Further improvements can be made, however, to increase overall yield especially for difficult to express proteins. In this study virus-derived silencing suppressors and replication elements were used …
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Production of recombinant human serum albumin in transgenic plants and plant cells
Humanserumalbumin(HSA)is the most abundant protein in the circulatory system. The principal function of HAS is to transport fatty acids, but it is also capable of binding agreat variety of metabolites and drugs. The potential of HAS in various applications, like usage as a plasma expander, …
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Physcomitrella patens (Hedw.) B.S.G. als Bioreaktor : Proteinzielsteuerung und Produktion von rekombinantem humanem Blutgerinnungsfaktor IX
Das Kooperationsprojekt "Physcomitrella patens als Bioreaktor zur Produktion heterologer, pharmazeutisch relevanter Proteine" hat zum Ziel, das Laubmoos als Produktionssystem zu etablieren. Vorteile des Mooses gegenüber den zumeist verwendeten Säugerzelllinien liegen vor allem in seiner …
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Physcomitrella patens (Hedw.) B.S.G. als Bioreaktor : quantitative Promotoranalyse und Produktion eines komplexen humanen Blutgerinnungsfaktors
Die vorliegende Arbeit diente der Etablierung von Physcomitrella patens (Hedw.) B.S.G. als System zur Produktion rekombinanter Proteinpharmazeutika. <br>Um ein Produktionssystem für heterologe Proteine flexibel nutzen zu können, ist es notwendig, die Expressionseffizienz der Transgene zu …
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Pflanzenzellen als Produktionssystem zur Gewinnung von Interleukin-4 Doppelmutein (IL-4 DM)
The present study has emerged from the Bayer-FhG joint project on "A feasibility study for recombinant protein production in plants". Its objective was to analyse and evaluate the extent to which plant expression systems would be able to produce pharmaceutical proteins; the test protein chosen for …
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Generation and characterisation of plant produced recombinant antibodies specific to LHRH for treatment of sex hormone dependent diseases
Leutinising hormone releasing hormone (LHRH) is a hypothalamic neurohormone that plays a pivotal role in the endocrine control of reproduction. Acting through its high affinity receptors on pituitary gonadotrophs, it regulates the secretion of gonadotropins. Manipulation of the neuroendocrine …