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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 88 for “"molecular evolution"”.
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Molecular Evolution of Viruses
<p>Molecular evolution is the process of evolution at the scale of DNA, RNA and proteins. Our goal was to study molecular evolution of viruses with special reference to Influenza A Virus.</p> <p>The recent Influenza A/H1N1(2009) outbreak has been the focus of intense research because of its high …
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Molecular evolution of biological sequences
Evolution is an ubiquitous feature of living systems. The genetic composition of a population changes in response to the primary evolutionary forces: mutation, selection and genetic drift. Organisms undergoing rapid adaptation acquire multiple mutations that are physically linked in the genome, so …
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Molecular evolution following allopolyploidization in Gossypium
… why polyploidy is so important in plant evolution. In this dissertation, I use the cotton genus (Gossypium) as a model system to better understand several aspects of molecular evolution following polyploidization. Specifically, in chapter 2, I use genomic and transcriptomic data from …
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Navigating Molecular Evolution Using Substitution Mappings
… than might have been expected in the field of molecular evolution. Here, I first create a sequence simulator capable of generating true substitution mappings for simulated data under any time-reversible model in order to facilitate study of substitution mappings. I then investigate the utility …
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Molecular evolution of primates - featuring mobile elements
… zu rekonstruieren. Es konnten bereits einige evolutionäre Fragestellungen mit Hilfe der SINE-Integrationen innerhalb verschiedenster Vertebratengruppen geklärt werden. In dieser Arbeit wurden Fragestellungen innerhalb der Colobinen und Neuweltaffen bearbeitet. Es gibt nach wie vor kontroverse …
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Rates of Molecular Evolution and Phylogenomic Inference
… research is the analysis of variation in rate of evolution, both across a genome and between the genomes of species. In this study we explore the relationship between different types of rate heterogeneity. We develop several statistical methodologies to address issues associated with the …
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Molecular Evolution of Visual System Genes in Fishes
… or genomic changes open new avenues for evolutionary changes. Visual system proteins are thus attractive systems for molecular evolutionary analyses. This thesis presents a collection of evolutionary studies on two gene families, opsins and crystallins. Opsin proteins determine the …
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Molecular evolution of the p53 network in reptiles
<p>The p53 molecular network is a master regulator of how cells respond to DNA-damaging stresses. Its primary function is to respond to DNA-damage by several options: apoptosis, cellular senescence, and temporary arrest of cellular growth for DNA repair. The p53 network's tight regulation of …
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Molecular Evolution of Anthocyanin Biosynthesis in Morning Glories
… of adaptation has become a central focus of evolutionary biology, and the incorporation of increasingly sophisticated analytical tools from molecular biology has made identifying causal genes a practical reality. The work presented herein addresses the effects of pleiotropic constraint on …
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Yeast Chorismate Mutase: Molecular Evolution of an Allosteric Enzyme
… Theorie, dass das Hefeenzym durch gleichzeitige Evolution von Regulations- und Stabilisierungsmechanismen aus einem monomeren, unregulierten Vorläuferprotein entstanden ist, welches dem der Escherichia coli CM ähnlich war. Um weitere Erkenntnisse über die Prinzipien der Proteinstabilisierung zu …
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Molecular evolution of eye lens proteins: cryptic structures and functions
Contains fulltext : mmubn000001_073767174.pdf (Publisher’s version ) (Open Access)
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Evolution of the genus Aristolochia - Systematics, Molecular Evolution and Ecology
Evolution of Piperales – matK gene and trnK intron sequence data reveal lineage specific resolution contrast. Piperales are one of the largest basal angiosperm orders with a nearly worldwide distribution. The order includes three species rich genera, Piper (ca. 1,000 species), Peperomia (ca. …
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Increased genome sampling reveals novel insights into vertebrate molecular evolution
… distinct questions pertaining to vertebrate molecular evolution. Gene duplicability is the tendency to retain multiple gene copies after a duplication event. Various factors correlate with gene duplicability, such as protein function and timing of expression during development. The position …
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Molecular evolution of the cytochrome b gene among percid fishes
To better understand the evolution of the cytochrome b gene and its implications for evolutionary relationships among percid fishes, the entire cytochrome b gene (1,140 base pairs) was amplified via PCR using the tRNA flanking primers and sequenced. Twenty-two species were examined, including 20 …
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Molecular Evolution in non-bilaterian Metazoa with Emphasis on Phylum Porifera
… besitzen. Die Betrachtung der molekularen Evolution stellt hier deshalb eine wertvolle und unabhängige Methodik dar. In der vorliegenden Arbeit wurde die molekulare Evolution dieser Tiere auf zwei verschiedenen Ebenen untersucht:1. Evolution von ribosomalen RNA (rRNA) Genen im Stamm …
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Organ-specific regulation and molecular evolution of the maize pericarp color1 gene
… pigmentation patterns. To elucidate the molecular basis of these allele-specific expression patterns, we characterized two novel P1-rw alleles, P1-rw1077 and P1-rw751::Ac. Structural analysis of P1-rw1077 indicated that this allele was generated by recombination between p1 and the tightly …
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Molecular evolution of the RNA polymerase genes and the phylogeny of seed plants
This work is a union of molecular biology and evolutionary biology in addressing questions regarding the evolution of organisms and their genes. This project focuses on major groups of seed plants (angiosperms, and four gymnosperms groups: conifers, cycads, Ginkgo and Gnetales). These organisms …
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Molecular evolution of a superfamily of chemoreceptors in Musca domestica and Ceratitis capitata
… appears to be a major driver for gene family evolution. Further exploration of these losses and expansions might ultimately lead to innovations in pest management and provide a base for which to further understand evolution of specialist versus generalist dipterans.
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Investigations into the molecular evolution of plant terpene, alkaloid, and urushiol biosynthetic enzymes
Plants produce a vast number of low-molecular-weight chemicals (so called secondary or specialized metabolites) that confer a selective advantage to the plant, such as defense against herbivory or protection from changing environmental conditions. Many of these specialized metabolites are used for …
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