Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 235 for “"molecular analysis"”.
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Molecular analysis of peasnRNA variants
… of the molecules. In light of this sequence analysis, it is clear that the dicot snRNA variants do not differ in sequences implicated in RNA:RNA interactions with pre-mRNA. Instead sequence differences occur in regions implicated in the binding of small ribonucleoproteins and may result in …
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Molecular analysis of wheat snRNAs
Pre-mRNA splicing is a complex event in which introns are removed and exons spliced together. This process is mediated by small ribonucleoprotein particles (snRNPs), formed from small nuclear RNAs (snRNAs) and their associated nuclear proteins.
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Molecular analysis of germ cell specification
The first step to ensure successful sexual reproduction and species survival is the correct differentiation of primordial germ cells (PGCs). PGCs are the first cells in the germline, and their correct specification is essential for the eventual production of gametes (eggs and sperm). Murine PGCs …
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Molecular analysis of vesicle biogenesis during autophagy
… GFP in the vacuole using immuno-western blot analysis. In this study a microscopic assay was established which supports the finding that PMN is efficiently inhibited in atg mutant cells. A nuclear resident fluorescent protein (NLS-mCherry) is used as marker protein. Part of this fluorescent …
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Microfluidic tools for molecular analysis and engineering
The shift of medical technology from a doctor's application of individualized medicine toward precision medicine has been accelerated by the advent of Next Generation Sequencing. Individualized medicine is where a doctor tries to understand the intricacies of a patient's medical state, where …
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Molecular analysis of cyanobacterial RNA polymerase genes
… are co-transcribed by another promoter. Northern analysis of Nostoc RNA revealed two transcripts (3.1 and 5.6 kb), which were specific for the rpoB and rpoC1C2 genes, respectively. SDS-PAGE, Coomassie staining and immunoanalysis detected two polypeptides with molecular weights of 72 and 94 kd when …
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Identification and Molecular Analysis of Dna In Exosomes
… by damaged cancer cells, and provide a potential molecular mechanism of action via the shuttling of activated DDR pathway proteins.</p>
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Molecular analysis of the salmon pathogen Piscirickettsia salmonis
… size from 0.4 to 3.5kb were detected. Sequence analysis of two inserts showed that the expected EcoRI site in pExCell recombinants was corrupted to the sequence CCATTC or GCGTTC. Limited sequence analysis of inserts revealed very high identity with E. coli gene sequences in the databases, and …
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Pathological, Immunohistochemical and Molecular Analysis of Recurrent Glioblastoma
… clinical and pathologic parameters, a survival analysis was performed and correlations between histopathologic parameters and each ancillary test were assessed. Among clinical parameters, age greater than 60 years was associated with decreased survival (p = 0.022) but other clinical parameters …
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Molecular analysis of sex chromosome evolution in papaya
… This study provides the first detailed analysis of the sex-specific regions of a plant sex chromosome pair. Sex chromosomes evolve from an autosomal chromosome pair through suppression of recombination between the two. Though signs of Y evolution are distinct, with the expansion of the Y …
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Genetic and molecular analysis of aging in yeast
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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Microfluidic Engineering for Ultrasensitive Molecular Analysis of cells
… technology for ultrasensitive and fast molecular analysis of cells. Chromatin immunoprecipitation (ChIP) assay followed by next generation sequencing serves as the primary technique to characterize the genomic locations associated with histone modifications. However, conventional …
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Molecular Analysis of Phenotypic Diversity in Human Fungal Pathogens
… Second, I characterized the role of the molecular chaperone Hsp90 in drug resistance and morphogenesis in an emerging fungal pathogen, Candida auris. I showed that fluconazole resistance of C. auris was independent of HSP90 expression, but in part mediated by the ABC transporter CDR1. …
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Cytogenetic and molecular analysis of follicular non-Hodkin's lymphoma
The incidence of the reciprocal translocation t (14;18)(q32;q21) in follicular lymphoma varies from 50% to 90% in American series. In the largest series from Europe, the translocation was present in only 21/51 (41%) of cases. The wide variety in incidence may in part be due to the method of …
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