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Showing 1 to 3 of 3 for “"modified lipoproteins"”.

  1. Markers and mechanisms of pre-eclampsia in pregnancies complicated by diabetes

    … aim of this thesis was to investigate whether modified lipoproteins and/or elevated glucose have a role in pre-eclampsia in pregnancies complicated by diabetes.<br/><br/>Trophoblast cell lines HTR8/SVneo and JAR were exposed to native LDL (N-LDL) vs. ‘highly-oxidized glycated’ LDL (HOG-LDL) …

    qu-belfast Repository record for Markers and mechanisms of pre-eclampsia in pregnancies complicated by diabetes (opens in a new tab)

  2. Investigating iPSC-Derived Macrophage Stimulation with Oxidised Low-Density Lipoprotein as an Effective In Vitro Model of Foam Cells in Atherosclerosis

    … respond by ingesting large quantities of the modified lipoproteins, such as oxidised low-density lipoproteins (oxLDLs), which are then metabolised to release cholesterol and cholesterol esters for use or recycling. Chronic uptake of modified particles eventually reduces the ability of …

    cambridge Repository record for Investigating iPSC-Derived Macrophage Stimulation with Oxidised Low-Density Lipoprotein as an Effective In Vitro Model of Foam Cells in Atherosclerosis (opens in a new tab)

  3. Plasmacytoid dendritic cells and neutrophils : underestimated cell populations during the onset of atherosclerosis

    … secretion. Thus, chronic stimulation of pDCs by modified lipoproteins and autoimmune mechanisms may critically drive inflammation in atherosclerosis.

    aachen Repository record for Plasmacytoid dendritic cells and neutrophils : underestimated cell populations during the onset of atherosclerosis (opens in a new tab)