Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"modified LDL"”.
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Markers and mechanisms of pre-eclampsia in pregnancies complicated by diabetes
… aim of this thesis was to investigate whether modified lipoproteins and/or elevated glucose have a role in pre-eclampsia in pregnancies complicated by diabetes.<br/><br/>Trophoblast cell lines HTR8/SVneo and JAR were exposed to native LDL (N-LDL) vs. ‘highly-oxidized glycated’ LDL (HOG-LDL) …
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Modification of Low Density Lipoprotein and the Effects of Modified Low Density Lipoproteins on the Endocytic and Secretory Repertoire of the Macrophage
… two aspects of the complex interaction between modified low density lipoprotein (LDL) and macrophages in the initiation and development of the atherosclerotic lesion. The first of these concerns the observed biological modification of LDL that leads to its subsequent enhanced uptake by …
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Chlamydia pneumoniae, Toll-like Receptors and Pathogenesis of Atherosclerotic Heart Disease
… in the presence of low-density lipoprotein (LDL). Toll-like receptors (TLRs) play a central role for macrophages to detect pathogens and elicit inflammatory responses.</p> <p>Data presented in this study have furthered our understanding of the different mechanisms of foam cell formation …
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Effect of Medicinal Herbal, Panax Notoginseng, on the Fate and Function of Professional Antigen Presenting Cells
… Furthermore, the uptake of FITC-conjugated modified LDL was reduced in notoginseng treated DCs. However, T cell proliferation in response to notoginseng treated-antigen-loaded DCs was not affected in vitro or in vivo. Mechanistically, notoginseng reduced nuclear levels of the transcription …
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Effect of Medicinal Herbal, Panax Notoginseng, on the Fate and Function of Professional Antigen Presenting Cells
… Furthermore, the uptake of FITC-conjugated modified LDL was reduced in notoginseng treated DCs. However, T cell proliferation in response to notoginseng treated-antigen-loaded DCs was not affected in vitro or in vivo. Mechanistically, notoginseng reduced nuclear levels of the transcription …