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Showing 1 to 20 of 48 for “"model membranes"”.
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Tastant interactions with model membranes
… solution and in solution with liposomes, a model membrane system. The observed changes in T1, values are analysed to determine which regions of the tastants are involved in the interaction with the membrane. In Chapters 4 and 5 an investigation is reported of the interaction of tastants with …
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Model membranes grafted with long polymers
Wir untersuchen, welchen Einfluss die Verankerung von langen, hydrophilen Polymeren in Lipidmembranen auf deren elastische Eigenschaften ausübt. Theoretisch werden zwei Grenzbereiche für die spontane Krümmung der Membran erwartet: i) bei kleinen Oberflächenkonzentrationen des Polymers (Pilzgebiet) …
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Model Membranes: Knudsen Flow Through Microcapillaries
Made available in DSpace on 2015-05-12T22:32:05Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7212212.PDF: 4389136 bytes, checksum: e1043406d90f19dbba9e513e496c003b (MD5) Previous issue date: 1971
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High-pressure NMR studies of model membranes
… explanation of the results, using a well-known model of cross-relaxation in the lipid bilayer, was that high pressure causes an increase in the order parameter throughout the acyl chains, directly increasing the measured cross-relaxation rate and steady-state value of the NOE.
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Biophysical Studies of Cholesterol in Unsaturated Phospholipid Model Membranes
<p>Cellular membranes contain a staggering diversity of lipids. The lipids are heterogeneously distributed to create regions, or domains, whose physical properties differ from the bulk membrane and play an essential role in modulating the function of resident proteins. Many basic questions …
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The interaction of antimicrobial peptides with lipopolysaccharide aggregates and model membranes.
… experiments on monolayer and bilayer membrane models containing dierent chemotypes of LPS were performed in the presence of the peptides; the data revealed that the two peptides have different mechanisms of interaction with membrane models containing LPS. These investigations provide new …
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High-resolution nuclear magnetic resonance studies of lipids and model membranes
… resonance (NMR) techniques to the study of model and biological membranes. Since the resolution of $\sp1$H and $\sp{13}$C MASS NMR spectra from multilamella and hexagonal-II phase is the same or even better than that obtained with sonicated liquid-crystalline system, the dynamics of …
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The structural effects of divalent cations and insulin on phospholipid model membranes /
It is well accepted that structural studies with model membranes are of considerable value in understanding the structure of biological membranes. Many studies with models of pure phospholipids have been done; but the effects of divalent cations and protein on these models would make these studies …
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High-pressure NMR studies of model membranes and Kramers turnover on solution
… and various relaxation times of phospholipid model membranes DPPC in multilamellar dispersions and in unilamellar vesicles have been investigated by using $\sp{31}$P NMR, $\sp2$H NMR, as well as one and two dimensional $\sp1$H NMR techniques in both the liquid crystalline and various gel …
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Studies of the orientational order and bilayer thickness in biological and model membranes
… methods for a range of Acholeplasma laidlawii membranes containing exogenously incorporated perdeuteriated palmitic acid and a second fatty acid of increasing unsaturation. The microorganism was grown under conditions where de novo fatty acid biosynthesis was suppressed. At 37°C, the growth …
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NMR Studies on Model Membranes. Interaction with Metal Ions, Ionophores and General Anaesthetics
… technique and current progress in the field of model and biological membranes was given. In chapter 2 it was shown that pulsed NMR techniqes gave insight to the effects of calcium, magnesium and lanthanide ions on the motional and physical properties of phospholipid molecules in …
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Fragments of the human antimicrobial LL-37 and their interaction with model membranes
… The interaction of the two fragments with model membranes was systematically studied in this work to understand their mode of action. Planar lipid films were mainly applied as model systems in combination with IR-spectroscopy and X-ray scattering methods. Circular Dichroism spectroscopy in …
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Solid-state NMR spectroscopy applied to model membranes: effects of polyunsaturated fatty acids
… the body is not completely understood. One model that has emerged from biochemical and imaging studies of cells suggests that n-3 PUFAs are taken up into phospholipids in the plasma membrane. Thus the focus here is on the plasma membrane as a site of potential structural modification by DHA. …
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Model Membranes Study the Lipid-Reactivity of HIV-1 Antibodies and Vaccine Antigen
… however, little is known about how lipid membranes contribute to NAb-antigen binding. To this end we have developed model membrane systems to study NAb and antigen lipid interactions. </p><p>We first created a surface plasmon resonance (SPR) spectroscopy based assay that monitors antibody …
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A critical analysis of the 2H NMR data in chlorhexidine-containing model membranes
… the internal molecular motions of phospholipid model membranes. Mixtures of dimyristoylphosphocholine (DMPC) and chlorhexidine (CHX) were investigated at several DMPC:CHX molar ratios (1:0,10:1,3:1). Extensive numerical analysis of previously acquired data identi ed the di erences in the …
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Spatial correlation of lipid phase fluctuations in model membranes studied with two-photon fluorescence microscopy
… fluctuations and the spatial organization of model lipid membranes was studied using Two-photon excitation fluorescence microscopy. Lipid membranes of different composition were reconstituted in Giant Unilamellar Vesicles (GUVs) and labeled with the environment sensitive dye LAURDAN whose …
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A study of the effect of anaesthetic molecules on model membranes formed in surfactant / water mixtures
… of a range of general and local anaesthetics on model membranes, aiming to establish if the addition of anaesthetic promotes changes in the membranes interfacial region or within their internal structure. The models used for biological membranes were simple surfactantiwater systems, which have …
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Theory of the general orientation dependence of ²H NMR spin-lattice relaxation and experiments on model membranes
… fast on the NMR timescale were investigated, model-independently, in the acyl chain and headgroup of phospholipids in the liquid crystalline phase. The general orientation dependence of spin-lattice relaxation of spin-1 nuclei interacting via fluctuating quadrupolar interactions was considered …
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Effect of the position of the double-bond in monounsaturated phospholipids on the dynamics of model membranes
Therllloelynalllics of lllodel 11lel1ll)rane systeills containing 1110nollnsaturatecl I)lloSI)holil) ids is strongly infllienced l)y the I)osition of the C==C dOlll)le })ond in tIle acyl chain. The telllI)eratllres of both chain-nlelting (TM) and La -+ HI! (TH) I)hase traIlsitions are lowered by …
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