Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"mobile element"”.
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Fluid-mobile element cycling (halogens, boron, lithium) and sourcing through the Costa Rican convergent margin
… in convergent margins can be traced using fluid-mobile elements such as Cl, Br, I, B, and Li. However, previous studies have often overlooked the forearc. Describing fluid loss from subducting oceanic crust to the forearc is difficult for several reasons including differences in pathways due to …
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Complete computational sequence characterization of mobile element variations in the human genome using meta-personal genome data
… structural variants (SVs) and in particular mobile elements insertions (MEIs). Moreover, almost all these methods can detect only the breakpoints of an occurred SV, sometimes with approximation, and do not provide complete sequences representing the SVs. The main objective of our research is …
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Following the LINEs (Long INterspersed Elements): human specific L1 elements and their orthologous loci in non-human primates
The L1 Ta subfamily of Long INterspersed Elements (LINEs) consists exclusively of human-specific L1 elements with a copy number of ~520 in the human genome. Four hundred sixty-eight L1 Ta elements were extracted from the draft human genomic sequence and screened by polymerase chain reaction (PCR) …
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An analysis of human Alu element lineages
… are distinct groups of Short INterspersed Elements (SINEs) found exclusively in primates. These lineages are comprised of several distinct subfamilies, which contain elements that are evolutionarily-related because they share common diagnostic mutations. Some of these Alu subfamilies are …
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The Transposon-Encoded Protein TnpB is an RNA-Guided Nuclease
… of programmable RNA-guided systems, the Obligate Mobile Element Guided Activity (OMEGA) family. This work serves as a window into the diversity of RNA-guided functions in nature and provides a rich source for future biotechnological development.
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Identification of differentially expressed genes in breast cancer tissues and cells
… Line 1 retrotransposon (Ll). Ll is a poly-A mobile element, and its insertion into functional genes has been implicated in human diseases, including breast cancer, however its role in breast cancer is not clear. To determine the locale and expression of galectin-3 and L1 in normal versus …
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Leveraging Genomic Information for Safer Gene Therapy
… genomic safe harbor (GSH) sites and insulator elements to ensure safe and stable transgene integration without disrupting the host transcriptome. Here we developed a knowledge-based approach using common polymorphic mobile element insertions (pMEIs) along with epigenetic and 3D chromatin …
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Data-driven approaches towards understanding trace metal and magmatic processes in arc volcanoes, with applications to Java, Indonesia
… specific mineral reactions are driving fluid mobile element enrichment in arc magmas and how does this vary from arc to arc? A later chapter asks: what petrological processes favor the enrichment of copper and the optimization of ore-forming potential in a magma? These global insights are …
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Genomic changes underlying disease resistance and high protein QTL
… form, potentially through the excision of a mobile element, producing seed with higher protein levels.
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Movement and Stability of the Staphylococcal Cassette Chromosome mec among Staphylococcus aureus
… these reports preceded discovery of SCCmec elements. Furthermore, stability studies did not fully characterize the loss of methicillin resistance by molecular means. |Thus, I undertook the studies found in Chapter 2 to confirm and clarify the conditions promoting transduction of SCCmec in S. …
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Characterization of the Factors Associated with SCCmec Mobility in Staphylococcus Aureus
… strains with type IV SCCmed did not excise their element. These strains are all highly related and represent a lineage of successful community associated pathogens. In addition, the inability to excise SCCmec in these strains is associated with the presence of a presumptive mobile element …
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BIOMINERALIZATION AND GLOBAL CHANGE: BIOTIC RESPONSE TO THE GONDWANAN GLACIATION AND SUBSEQUENT CLIMATE WARMING
… on the calcite shell remains. Boron is a highly mobile element that can be used as a tracer of imprint of diagenetic alteration on fossil shells (Joachismki et al., 2005). The results of these analyses show that silicifica-tion can affect in different ways the brachiopod shells, and three …