Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"mitotic fidelity"”.
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The effects of chromosome number changes on mitotic fidelity and karyotype stability
The correct number of chromosomes is important for the maintenance of healthy cells and organisms. Maintenance of a correct chromosome number depends on the accurate distribution of chromosomes to the daughter cells during cell division, and errors in chromosome segregation result in abnormal …
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De novo synthesis of high purity CD3 epsilon peptides utilizing SUMO expression system in bacteria
… are expressed in E. coli cells with an SMT3 (Mitotic Fidelity Gene 3) tag. Subsequently, SMT3 tag is removed with SUMO protease and the resulting peptide is further purified. This novel in vitro approach results in high yields of non-modified peptides with great purity (>95%).
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Determining how variations in cell and nuclear size contribute to mitosis and tumorigenicity in cancer cells that undergo whole genome doubling
… in cell and nuclear size after WGD affect mitotic fidelity and tumorigenic potential. I show that cell and nuclear size do not always scale with DNA content in cancer cells that undergo WGD, resulting in 4N cancer cells that vary in size. With this experimental system, I demonstrate that …