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Showing 1 to 2 of 2 for “"mitochondrial genetic bottleneck"”.
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Theoretical and Statistical Approaches to Understand Human Mitochondrial DNA Heteroplasmy Inheritance
Mitochondrial DNA (mtDNA) mutations have been widely observed to cause a variety of human diseases, especially late-onset neurodegenerative disorders. The prevalence of mitochondrial diseases caused by mtDNA mutation is approximately 1 in 5,000 of the population. There is no effective way to treat …
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Insights Into Mitochondrial Genetic and Morphologic Dynamics Gained by Stochastic Simulation
… involved are not completely understood. The mitochondrial genetic bottleneck has puzzled biologists for a long time. Approximate models of genetic bottleneck proposed in the literature do not accurately model underlying biology. Recent studies indicate mitochondrial morphology changes during …