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Showing 1 to 1 of 1 for “"mito UPR"”.

  1. The Transcription Factor ATF5 Protects Cortical Neurons from Toxicity Induced by Prostaglandin J2

    <p>Mitochondrial dysfunction has been recognized to play a central role in the pathogenesis of neurodegenerative disorders, including Parkinson’s and Alzheimer’s disease. Transcription factor ATF5 has been shown to mediate an endogenous stress pathway known as the UPR<sup>mt</sup>, a prosurvival …

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