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Showing 1 to 20 of 23 for “"milk oligosaccharides"”.
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Metabolism of human milk oligosaccharides by infant-associated bifidobacteria
… metabolise specific glycans only found in breastmilk, and indigestible for the infant, known as Human Milk Oligosaccharides (HMOs). Fascinatingly, the adaptation to utilise HMO as a substrate by bifidobacteria is almost exclusively reserved for infant-associated species, and even more …
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Probiotic metabolism of human milk oligosaccharides (HMOs) and prebiotics
Human milk contains a high concentration of complex oligosaccharides (HMOs) that are believed to confer physiological benefits to infants such as immunomodulation and prevention of pathogen attachment. In addition, it has been postulated that HMOs serve as prebiotics by promoting the growth of …
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The role of probiotics, prebiotics, and human milk oligosaccharides in infant formulae
… and only 44% of infants receive human milk to any extent at six months of age (Gartner et al., 2005; Li et al., 2005; Eidelman et al., 2012). Nearly 40% of infants receive formula as their sole source of nutrition by one month of age (Li et al., 2005). Probiotics and/or prebiotics are …
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Detection of colorectal carcinoma-associated antigens using specific antibodies against human milk oligosaccharides
Rabbit antibodies against human milk sialyltetrasaccharide b Galßl—3[NeuAca2—6]GlcNAcßl—3Galßl—4Glc) and sialyltetrasaccharide a (NeuAca2-3Ga|ßl·3GlcNAcß1-3Galßl-4Glc) were used to detect their homologous haptens as gangliosides in the human colorectal carcinoma cell line SW'lll6. …
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COMPARATIVE GENOMICS AND FUNCTIONAL ANALYSIS OF BIFIDOBACTERIUM CARBOHYDRATE ACTIVE ENZYMES IN HUMAN MILK OLIGOSACCHARIDES UTILIZATION
… multiple determinants such as birth mode, breastmilk feeding practices, and the environment. Previous studies have identified specific taxa associated with protection from atopy and asthma including Bifidobacterium. Human Milk Oligosaccharides (HMOs) are an abundant component of breastmilk; …
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Bifidobacterial interactions with human milk oligosaccharides and their combined potential for the advancement of infant nutrition
… research was to investigate the role of human milk oligosaccharides (HMOs) in shaping the infant gut microbiota and in supporting immune health. HMOs are complex carbohydrates found at high concentrations in human breast milk, where they confer various critical functions. Despite their …
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Maternal stress signature and infant neurodevelopment: determining the beneficial effects of human milk oligosaccharides - an in vitro study
Human Milk Oligosaccharides (HMOs), the third most abundant solid component of breast milk, are becoming increasingly popular as their role in human health is further understood. In breastfed infants, HMOs play roles in many essential functions, including shaping the gut microbiota, inhibiting …
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Human milk oligosaccharides: Maternal determinants and effects on infant gut microbiome, and infant cognitive and behavioral development during early life
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-05-01
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Colonization dynamics of oro-gastrointestinal microbes critical to infant health
… the community. It is well-known that breastmilk contains oligosaccharides that promote the growth of bifidobacteria. However, formula-fed infants lack access to these carbohydrates and have a delayed establishment of bifidobacteria. Therefore, infant formula companies began supplementing …
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A nutriceutical approach to inhibiting H1N1 influenza infection
… is clearly due to the immune component of breast milk; however, the non-immune component, especially human milk oligosaccharides (HMO) are also thought contribute to antimicrobial activity. Human milk containsa large variety of oligosaccharides, some of which are present in sufficient …
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Metabolism of host-derived carbohydrates by Bifidobacterium breve UCC2003
… monosaccharide, which is found in human milk oligosaccharides (HMOs) and the mucin glycoprotein. B. breve UCC2003 was also shown to cross-feed on sialic acid released from 3’ sialyllactose, a prominent HMO, by the extracellular sialidase activity of Bifidobacterium bifidum PRL2010. …
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Production of a functional human milk oligosaccharide, 2'-fucosyllactose, using microbial cell factories
Human breast milk is the gold standard for infant nutrition. In human milk, the oligosaccharides may protect babies by acting as decoy receptors for pathogens. Also, human milk oligosaccharides (HMOs) enhance the proliferation of probiotics to strengthen the host immune system. Among HMOs, …
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Phylogenetic and functional characterization of human microbiome intra-species diversity and tracking of early-life transmission
… especially the ability to feed on Human Milk Oligosaccharides. These differences in metabolism between strains were also observed by their respective empirical growth rate that was seen associated with transmission and persistence in the infant gut. To further systematically assess the …
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Unravelling the impact of early-life nutrition on microbiota-gut-brain axis signalling
… early-life dietary intervention with human milk oligosaccharides (HMOs) and prebiotics was investigated on its ability to reverse the effects of antibiotic-induced microbiota depletion on brain transcriptome and behaviour in juvenile male mice. The combination of HMOs with prebiotics led to …
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Human milk oligosaccharide supplementation did not affect gut development in the healthy neonatal piglet
… if the infant is not breast-fed. Breast milk is superior to infant formula in multiple ways, one of the advantages being the human milk oligosaccharide (HMO) content. HMO is beneficial for the immune health of the baby and cultivating a healthy gut microbiota population. It also has the …
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Effects of 2ʹ-fucosyllactose on brain and cognitive development of intrauterine growth restricted piglets
… impairments that persist into adulthood. Human milk oligosaccharides (HMO) have been postulated to exert positive effects on brain development. HMOs are the third most abundant solid component of breast milk with 2′-fucosyllactose (2′FL) being the most abundant HMO. We aimed to determine whether …
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Technical and economic viability of value added product recovery in the corn dry grind ethanol process
… (2’-FL) is one of the most abundant human milk oligosaccharides and has been linked with reduced risks of fatality and intestinal dysfunction in infant piglets. However, high costs associated with synthesis and purification restrict its commercial production. Distillers dried grains with …
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Impact of formula additives on immune and gastrointestinal development in the piglet
… (βG), nucleotides (NT), and human milk oligosaccharides (HMO) could stimulate the development of the neonatal immune and gastrointestinal systems. Dietary βG are able to boost the natural defense mechanism by stimulating both innate (Descroix et al., 2006) and adaptive immune …
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Dietary Manipulation at Pre-Conception and During Development Influence Metabolism and Gut Microbiota in Rats
… were to determine: 1) the impact of human milk oligosaccharide (HMO) supplementation on health status in weanling rats; 2) the impact of a paternal high protein (HP) diet on offspring metabolic health; 3) whether supplementation of a methyl donor cocktail (HF/S+M) before conception …
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Effects of early nutrition on the wnt and bone morphogenic protein pathways in the developing intestine
… compounds that are naturally occurring in breast milk. Because of this, there has been an increased interest by the companies that manufacture infant formula to include additives that would potentially allow formula to more closely mimic breast milk activity. One such ingredient currently being …
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