Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"mifepristone"”.
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Differential Endometrial Responses of Primates vs Rodents: Screening for Antiproliferative Effects of Antiprogestins
<p>The antiprogestin, mifepristone, has previously been shown to noncompetitively inhibit estrogen-induced endometrial proliferation in nonhuman primates (van Uem et al., 1989; Wolf et al., 1989b; Neulen et al., 1990; Neulen et al., 1996). For both economical and ethical reasons, we are encouraged …
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Inducible Gene Expression in Cell Cultures and in Microencapsulated Cells
<p>The mifepristone-regulated transcriptional activation system provides a means to exogenously control gene expression in transformed mammalian cells in a temporal and spatial fashion. Such a promoter activation system consists of three components: The first of these is a steroidal inducer drug, …
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Strengthening medical abortion in South Africa
… experiences following the introduction of mifepristone into second trimester medical abortion services. Published or submitted papers included in this thesis are from four prospective studies evaluating interventions and interviewing women and health care workers in South African public …
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Influence Of Previous Cesarean Section On Clinical Outcome Of Medication Abortion
… The protocol for medication abortion was 200mg Mifepristone orally followed by 400mcg of misoprostol vaginally or buccally administered 12-24 hours later. Failure was defined as positive pregnancy test at follow-up. Demographic and outcome data was collected from patient self-report …
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Alterazioni indotte dall'isolamento sociale sulla regolazione a feedback negativo dell'asse ipotalamo-ipofisi-surrene
… GR function by blockade these receptors with mifepristone (a non-selective GR antagonist) in control group-housed animals and we have measured the expression of hypothalamic α4 and δ GABAA receptor subunits in basal condition and allopregnanolone (AP) levels after stress exposure. Socially …
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Discovering the biological and clinical implications of modulating glucocorticoid action using metabolomic profiling of human plasma samples
… 2 diabetes given either placebo or metyrapone +mifepristone (‘glucocorticoid blockade’) for 12 hours. In the second study, 20healthy men were given metyrapone with either low or high doses of insulin, plussuch a dose of hydrocortisone as to achieve low, medium or high plasma cortisollevels. …
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Medikamentinio nėštumo nutraukimo aspektai Lietuvoje /
… databases using the keywords: medical abortion, mifepristone, misoprostol, adverse effects, complications, with the inclusion criteria: publication date 2019 to 2024, publications in Lithuanian and English languages. Results. Data were collected from 355 women. Findings revealed that slightly …
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ETHANOL REGULATION OF GLUCOCORTICOID RESPONSIVE GENES
… responses to ethanol. Adrenalectomized (ADX) and mifepristone (RU-486) both impaired acute ethanol (2 g/kg) induced locomotor activation in DBA/2J mice without affecting basal locomotor activity. ADX mice showed microarray gene expression changes in the PFC that significantly overlapped with acute …
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The role of amygdala-based caspase-1 activation in regulating the behavioral response to allostatic stress
… but not the glucocorticoid antagonist mifepristone was able to ameliorate memory deficits and neuroinflammation following stress. Further, we demonstrate that extracellular adenosine acts as critical danger signal mediating the effects of stress on inflammasome activation and memory …