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Showing 1 to 2 of 2 for “"middle-down proteomics"”.
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Development and application of OmpT-based middle down proteomics
… functioning of a biological system. The goal of proteomics is to provide such information as protein identities, post-translational modifications (PTMs) on proteins, and ultimately, quantification of proteins or their PTM levels from given biological samples, mostly using mass spectrometry. …
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Development and Application of Next Generation Mass Spectrometry for Protein Analysis at High-Resolution
… modifications on a high throughput basis. Called Middle Down Proteomics, this process identified 7454 peptides from 2-20 kDa (1472 unique) from 555 proteins after just 23 LC-MS/MS injections. Along with greatly increased confidence for peptide identification (expectation values from 10-89 to 104) …