Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"microvessel density"”.
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Impact of Caveolin-1 Expression and Microvessel Density on the Prognosis of Upper Urinary Tract Transitional Cell Carcinoma
… the relationship of caveolin-1 expression and microvessel density (MVD), a reflection of angiogenesis, with prognosis in patients with UUT-TCC. MATERIALS AND METHODS: Formalin-fixed, paraffin-embedded tissue sections of UUT-TCC from 98 patients who had undergone radical nephroureterectomy were …
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Correlation of Cyclooxygenase-2 and Microvessel Density with Prognosis in Transitional Cell Carcinoma of the Upper Urinary Tract
… study, the relationship of COX-2 expression and microvessel density (MVD), a reflection of angiogenesis, with prognosis in patients with transitional cell carcinoma of the upper urinary tract was investigated. MATERIALS AND METHODS: Formalin-fixed, paraffin-embedded tissue sections of …
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Cancer Associated Fibroblast Derived Angiogenic Factor Mfap5 In Ovarian Cancer Progression
… between stromal MFAP5 expression and intratumor microvessel density, suggested a pro-angiogenic role of MFAP5. This study aims at delineating the functional roles and mechanisms by which stromal MFAP5 modulates ovarian tumor progression and angiogenesis and investigating the potential of …
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Correlation of HAS2-associated gene duplications with biological aggressiveness of mast cell tumors in Chinese Shar-Pei dogs
… of cutaneous mucinosis, depth of invasion, and microvessel density (MVD). Shar-Pei and non-Shar-Pei MCTs were evaluated via qPCR for relative copy number of the gene duplication upstream of HAS2. The proportion of grade III tumors was significantly higher in Shar-Pei than the general canine …
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Μελέτη της κλινικής σημασίας της αγγειογένεσης σε ασθενείς με νόσο hodgkin
… evaluate various morphometric characteristics of microvessels, highlighted by means of anti-CD34 immunohistochemistry, in the lymph node of 286 patients with HL at diagnosis and investigate their relationship with several clinicopathologic parameters and prognosis. EXPERIMENTAL DESIGN: …
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Paxillin-dependent control of tumor angiogenesis
… the mechanism by which it contributes to normal microvessel network formation and tumor angiogenesis. I found that paxillin knockdown increases microvessel density but causes loss of sprout orientation. These characteristics resemble those of tumor vasculature, and, in fact, studies revealed that …
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Stem cell based therapy of malignant brain tumors
… MSC implantation did not, however, affect tumor microvessel density or the survival of glioma-bearing animals. In summary, gliomas can attract endogenous striatal neuroblasts from the SVZ. However, intratumoral implantation of NPCs and MSCs yields a much more powerful, and tumor-specific, …
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A Hierarchical Image Processing Approach for Diagnostic Analysis of Microcirculation Videos
… automatically or accurately. In particular, microvessel density has been a critical diagnostic measure in evaluating disease progression and a prognostic indicator in various clinical conditions. As a result, automated analysis of the microcirculatory system can be substantially beneficial in …
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Targeted Inhibition of Sp1 Transcription Factor and Anti-Angiogenesis of Human Pancreatic Cancer
… implications. Sp1 and VEGF expression and microvessel density (MVD) were analyzed using pancreatic cancer patients specimens through immunohistochemistry staining. The impact of Sp1 expression alternation on angiogenesis and tumor progression in nude mice were determined by knockdown Sp1 …
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Role of the Activin/Follistatin system during angiogenesis and tumor progression
… analysis of human tumors. Correlation of high microvessel density (MVD) with increased tumor growth, tumor aggressiveness and poor patient prognosis has been shown for many tumors, emphasizing the importance of increased angiogenesis in tumor progression. Results of tumorigenesis experiments …
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Therapeutic Aerobic Exercise in a Mouse Model of Breast Cancer: Effects on Tumor Progression, Angiogenesis, and Response to Chemotherapy
… implantation caused significant increases in microvessel density (CD31) and vessel maturity (colocalization of CD31 with NG2 and desmin). Hypoxia (EF5) was significantly reduced in the exercising animals, and MRI showed that tumors were more uniformly perfused in the running groups. …
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Stromal Derived Growth Factor Alpha (Sdf-1Α) Induces The Differentiation of Bone Marrow Progenitor Cells (Bmcs) Into Pericytes By Regulating Platelet Derived Growth Factor B (Pdgf-B) Transcription
… the tumor microenvironment decreased the tumor microvessel density, decreased the tumor blood vessel perfusion and, increased tumor cell apoptosis. We then analyzed the effect of AMD3100 on vasculogenesis of Ewing’s sarcoma and found that BMCs migrated to the tumor site where they differentiated …
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The Role of Platelets In Ovarian Carcinoma
… Platelet depletion also significantly decreased microvessel density and pericyte coverage (p<0.001). Platelet counts increase by 31-130% in mice with invasive ovarian cancer compared to controls (p<0.01) and strongly correlate with mean megakaryocyte counts in the spleen and bone marrow (r=0.95, …
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Exploiting Optical Contrasts for Cervical Precancer Diagnosis via Diffuse Reflectance Spectroscopy
… absorption contrast. The concomitant increase in microvessel density and [total Hb] suggests that both are reactive to angiogenic forces from up-regulated expression of VEGF in CIN 2+. Masson's trichrome stain was used to assess collagen density changes associated with dysplastic transformation of …
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Untersuchung der Expression von Cyclooxygenase-2, VEGF und der Gefäßdichte im Nierenzellkarzinom
Die Cyclooxygenase-2 (COX-2) hat Einfluß auf die maligne Transformation von Zellen, deren Proliferation, Migration und Invasion ins Gewebe, auf die Apoptose und auf die Gefäßneubildung in Tumoren. Letztere ist bei der Tumorentstehung ein fundamentaler Prozeß, und VEGF nimmt unter den daran …