Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 104 for “"microparticle"”.
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Microparticle Influenced Electroosmotic Flow
<p>The influence of microparticles on electroosmotic flow was investigated experimentally and numerically. Experiments were conducted using four different particle types of varying chemical composition, surface charge and polarity. Each particle type was tested at five different volume fractions …
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Uniform biodegradable microparticle systems for protein delivery
… (PLG) and poly(lactic acid) (PLA) microparticles such as double-wall/monolithic microspheres and microcapsules have been heavily investigated for controlled delivery of small-molecule drugs as well as peptides, proteins and DNA. The size distribution of protein-loaded biodegradable …
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Mechanisms of microparticle release from human platelets
… vesicles, including platelet-derived microparticles that expose phosphatidylserine on their surface. This thesis aims to resolve the mechanisms by which pro-thrombotic microparticles are released from platelets, which have not been well-characterised. Experimental methods used include …
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Programmable Microparticle Scaffolds for Enhanced Diagnostic Devices
… E. Coli system and the creation of programmable microparticle scaffolds that may be controlled by biological circuitry. In particular, by leveraging the strong interaction between biotin and streptavidin, I have created programmable microparticle scaffolds capable of attenuating the intensity of …
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Microparticle retention aid systems in mechanical pulp suspensions
In this thesis, the effectiveness of microparticle retention aid systems comprising of different cationic starches (tapioca and waxy maize), cationic flocculants (flocculant 1, linear with low charge density and flocculant 2, branched with medium charge density polyacrylamides) and anionic …
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Characterization of microparticle velocities in converging-diverging nozzle systems
Present day flight vehicles are capable of reaching very high speeds and scientific literature suggests that atmospheric aerosols may cause damage to them. Ongoing work in particle impact damage modeling, aerosol deposition methods, and fundamental studies of particle impact dynamics require …
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The effect of precipitation techniques on bioadhesive microparticle characteristics
… was developed for preparing bioadhesive HPMC microparticles for nasal delivery. Aqueous gels of lactose:HPMC (1:1) were used as a model formulation, added to a precipitating solvent, and the effect of processing parameters such as stirring speed (1000-2000 rpm), needle gauge (19g, 21g and …
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Single microparticle electrophoresis to study polymer and nanoparticle adsorption
De wetenschappelijke interesse voor colloïdale deeltjes en de interactie van colloïdale deeltjes met andere micro- en nano-objecten (bvb nanodeeltjes, eiwitten of polymeren) is belangrijk in industriële processen en in farmaceutische toepassingen. Om verschijnselen waarbij colloïdale deeltjes …
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Development of Ultrasonic Devices for Microparticle and Cell Manipulation
… demand for the precise manipulation of cells and microparticles for applications in cell biology and analytical chemistry has driven recent development of ultrasonic manipulation technology. Compared to the other major technologies used for cell and particle manipulation, such as magnetic …
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Quantifying Plasticity and Temperature in High Velocity Microparticle Impacts
… to measure the dynamic yield strength of ductile microparticles, effectively removing the need for the tacit assumption that the properties of bulk materials can be imposed on powders despite differences in processing. The understanding of microstructure and particle behavior are then combined to …
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Electrohydrodynamic (EHD) printing of microparticle streams for additive manufacturing
… explores EHD printing of liquids containing microparticles. For printing, liquids containing microparticles with a diameter of ~1-10 pm are prepared, which sediment upon loading into the capillary tip. A single-tip EHD apparatus enabling pulsed delivery of kilovolt signals, high speed …
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Microfluidic processes to create structured microparticle arrangements and their applications
Multifunctional polymeric microparticles have shown the great potentials in a variety of fields. While the advance in particle synthesis allows for fine tuning of their physical properties and chemical functionality, particle manipulation is still appealing, but challenging issue in colloidal …
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Design and fabrication of an addressable MEMS-based dielectrophoretic microparticle array
(cont.) enough to conduct functional genetic surveys.
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Scalable development of multiplexed microparticle technologies for optical single-cell barcoding
The biological complexity of an organism arises from the diversity and interaction of individual cells. Optical imaging techniques with single cell resolution have played an invaluable role in developing an understanding of cellular identity and function. However, current imaging techniques, …
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Effect of Temperature on Microparticle Rebound Characteristics at Constant Impact Velocity
Many gas turbine engines operate in harsh environments where the engine can ingest solid particles. Particles can accelerate the deterioration of an engine and reduce the engine’s service life. Understanding particle interactions with the materials used in gas turbines, at representative engine …
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Magnetic microparticle trapping and mechanical excitation using domain walls in magnetic microstructures
We examined the feasibility of using the resonant frequency of magnetic bead-domain wall (DW) couples in a host fluid to measure particle size. Nickel-Iron (Permalloy) rings, made using electron beam lithography, served as the tracks for nucleating and moving DWs, and Invitrogen Dynabeads M-270 …
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A microparticle engineering approach to enhance the potency of mesenchymal stem cells
… of MSCs. Loading iron oxide nanoparticles in the microparticles resulted in enhanced tracking of MSCs by MRI from 6 days with nanoparticles alone to beyond 12 days with iron oxide microparticles. Finally, the novel discovery that glucocorticoid steroids significantly increase the immunomodulatory …
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PULMONARY DELIVERY OF PNEUMOCCOCAL VACCINE USING NANOCOMPOSITE MICROPARTICLE CARRIERS VIA DRY POWDER INHALATION
S. pneumoniae is one of the most significant human pathogens, causing high morbidity and mortality rates globally. Although there are vaccine available such as PPV 23, PCV7, PCV10, and PCV13, they are ineffective in some situations due to the differing epidemiology of various serotypes depending on …
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Experimental Investigation of Microparticle Sand Sticking Probability from 1000°C to 1100°C
… on statistically modeling the initial onset of microparticle deposits onto an analogous hot-section surface. Generally, as deposits accumulate onto a hot-section surface, the existing deposit formation is more likely to bond with incoming particulate at a faster rate than an exposed bare …
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A Systems Approach to the Modeling and Control of Molecular, Microparticle, and Biological Distributions
… takes the form of a distribution: molecular, microparticle, and biological distributions. This approach involves incorporation of sensor technology and experiments, model identification, simulation algorithm development, parameter sensitivity analysis, parameter estimation, model validation, …
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