Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"microdomain"”.
-
Field induced orientation of semicrystalline and non-crystallne block copolymer microdomain patterns
Various block copolymer microdomain structures are controlled in bulk as well as in thin film by employing flow fields, directional solidification, and substrates. In bulk systems, flow fields generated by the 'roll casting' process orient amorphous cylindrical microdomains along the flow direction …
-
Microdomain calcium oscillations in Drosophila glia regulate seizure susceptibility and require NCKX
… has been disputed. Recently, near-membrane microdomain Ca²+ transients were identified in fine astrocytic processes and found to arise via an intracellular store- independent process. Here, we describe the identification of rapid, near-membrane Ca²+ oscillations in Drosophila cortex glia of …
-
Single molecule tracking studies of solvent-swollen microdomains in cylinder-forming polystyrene-Poly (ethylene oxide) diblock copolymer films
Solvent swelling of block copolymer microdomains plays an essential role in the improvement of microdomain alignment by solvent vapor annealing and in chemical separations using block copolymer monoliths. Here, investigation of the effects of solvent swelling on the molecular permeability and …
-
Equilibrium and Dynamic Phase Behavior in Thin Films of Cylinder-Forming Block Copolymers
… theory to the treatment of cylindrical microdomains in a thin film, over the detailed analysis of the phase behavior and the microdomain dimensions of a cylinder forming model system, to the first in-situ measurements of phase transitions and microdomain dynamics in a thin block …
-
Host Entry Factors for Human Coronaviruses
… typically resides in a distinct cell surface microdomain from the host cellular receptor. However, viral binding triggers the relocalization of the protease to the same microdomain as the receptor, possibly allowing it to cleave the glycoprotein immediately after receptor binding.</p><p>While …
-
Regulation of Ras signaling and oncogenesis by plasma membrane microdomains
… the contributions of plasma membrane (PM) microdomain targeting to the functions of H-Ras and R-Ras. These paralogues have identical effector-binding regions, but variant C-terminal targeting domains (tDs) which are responsible for lateral microdomain distribution: activated H-Ras targets …
-
Organization of the Streptococcal ExPortal and its Interaction with Cationic Antimicrobial Peptides
… secretory translocons at a defined anionic lipid microdomain of the cytoplasmic membrane that is enriched for accessory factors needed for protein biogenesis, referred to as the ExPortal. The manner in which <italic>S. pyogenes<italic/> achieves and maintains spatial coordination of the factors …
-
Spatial organization of sodium calcium exchanger and caveolin-3 in developing mammalian ventricular cardiomyocytes
… is the structuring element for a restricted microdomain facilitating NCX-CICR, our results cannot rule out the existence of such microdomain organized by other anchoring proteins. The developmentally stable distributions of NCX and cav-3 imply that the observed developmental CICR changes are …
-
Cell-type specific contributions to Rett Syndrome : neuronal and astrocytic signaling and sensory processing
… visual cortex and my work reveals that discrete microdomain regions of visual cortex astrocytes also exhibit temporally reliable and spatially correlated responses to natural scenes. I show that glutamate transporters, which influence astrocytic Ca 2 signaling and synaptic transmission, regulate …
-
Functional Analysis of Drosophila Integrator Complex In Snrna 3' End Processing
… important functional interaction mediated by a microdomain within Integrator subunit 12 (IntS12) and IntS1 that is required for the activity of the Integrator Complex in processing the snRNA 3’ end. Through the development of a reporter-based functional RNAi-rescue assay in <em>Drosophila</em> …
-
Self-Assembly of Block Copolymers in External Fields
The influence of external fields on the microdomain structure of block copolymers has been studied. Both surface fields and electric fields have been considered. External electric fields are used to create macroscopically oriented bulk samples. In order to circumvent limitations associated with the …
-
Block copolymer photonic crystals : towards self-assembled active optical elements
… these primary objectives, control of thin film microdomain orientation and novel three-dimensional (3D) optical characterization of block copolymer photonic crystals have been also achieved, both of which can greatly help optimize the properties of block copolymer photonic crystals. First, a …
-
Deformation behavior of cylindrical block copolymer bicrystals : pathway to understanding block copolymer grain boundaries
… x-ray scattering (SAXS) was used to monitor the microdomain structural evolution. Finally, finite element simulations illustrated the state of strains of the bicrystal. The symmetric (45-45) bicrystal turns out to be the most complex system, despite of the simplest geometry.
-
Orientation and Phase Behavior of Block Copolymers in External Electric Fields
The influence of external electric fields on the microdomain structure of block copolymers has been studied. The results range from an analysis of the mechanism and kinetics of the reorientation process, via the discussion of the driving force, to first investigations on the influence of an …
-
Biophysical analysis of the spatial and temporal distribution of free Ca2+ ions within micro- and nanodomains of muscle cells
… permeable ion channels (RyRs). The recording of microdomain Ca2+ signals (spatially averaged measurements of transient increases in myoplasmic [Ca2+]), was achieved by epi-illumination microscopy utilizing changes in the absorption of the Ca2+ indicator Antipyrylazo III. Nanodomain Ca2+ signals, …
-
Sterol requirements in Drosophila melanogaster
… properties such as permeability, fluidity and microdomain formation. Drosophila is an excellent model system in which to study functional requirements for membrane sterol because, although it does not synthesize sterol, it nevertheless requires sterols to complete development. Moreover, …
-
Characterization of nano-arrays fabricated via self-assembly of block copolymers
… volume fractions of the blocks that allow sphere microdomain formation but of different molecular weights. The ultimate goals are to establish how the molecular weight of this block copolymer affects its self assembly on templated and on flat substrates and to use this factor as well as …
-
TEM/EDXS studies of phase separation in block and graft copolymers
… relationships between molecular parameters and microdomain formation of a variety of block- and graft-copolymers were studied by Transmission Electron Microscopy (TEM). Molecular variables included chemical composition: dimethyl-, fluoropropyl and diphenyl-siloxane , sulfone styrene, …
-
Fluorescence fluctuation spectroscopy and microscopy : application to cellular molecular dynamics and organization
… FCS data in order to resolve hIAPP-induced microdomain spatial organization and temporal dynamics in the cell membrane. Our analysis resolved the temporal evolution of multiple diffusing species in the spatially heterogeneous cell membrane, lending support to the "carpet model" for the …
-
Structure and properties of hydrogen and covalently bonded side group liquid crystalline block copolymers
… observation of a novel transverse cylindrical microdomain morphology in one case. The investigation of hydrogen-bonded side-group liquid crystalline block copolymers based on P(S-b-AA) followed a screening of several other candidate host diblock-mesogen pairs. The structure and thermal …
Page 1 of 2