Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"microcystins"”.
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Bioaccumulation of microcystins in terrestrial food plants and the development of novel sorbents for monitoring microcystins in irrigation water
… there have been evidence of the toxic effects of microcystins (MCs) and cylindrospermopsin (CYN) on terrestrial plants including plants used for food. Ever since, the use of surface waters contaminated with cyanobacteria and cyanotoxins for agricultural purposes has been receiving growing …
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Raman Spectroscopy for Monitoring of Microcystins in Water
… industry due to their capacity to produce microcystins and other cyanotoxins that are deadly to humans, livestock, pets, and aquatic life at low doses. Unfortunately, the strategies currently employed for cyanotoxin detection involve laborious analyses requiring significant expertise or …
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Investigations of microcystins (cyanobacterial peptide toxins) detection, purification and analysis.
… water blooms. This study was an investigation of microcystins, the cyclic heptapeptide toxins produced by cyanobacteria. The method of detection relied on high performance liquid chromatography (HPLC) analysis which led to the development of large-scale purification processes to provide material …
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Monitoring and regulating cyanobacterial metabolites (microcystins and geosmin) in aquatic systems.
… One of the most prominent cyanotoxins are microcystins and their sister compound nodularin. The biological role of microcystins is poorly understood. A pheromonal effect was observed applying a novel stable isotope labelling (15N) method. Microcystin- LR has been shown to stimulate culture …
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An investigation into factors influencing the production and degradation of microcystins.
Microcystins (MCYST) potently inhibit protein phosphatases and these cyclic heptapeptides are powerful hepatotoxins. They are known to be secondary metabolites produced by several species of cyanobacteria. The release of these peptides into water supplies poses a considerable threat to both humans …
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An investigation into the biodegradation of peptide cyanotoxins (microcystins and nodularin) by novel gram-positive bacteria.
Cyanobacterial secondary metabolites, microcystins (MC) and nodularin (NOD) have become common contaminants in most aquatic ecosystems over recent years presenting a hazard to animal and human health. Unfortunately, these chemically diverse peptide hepatotoxins remain a challenge to most …
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Pathways of Transport of Microcystin-LR from Microcystis aergonisa to the Benthic Environment
… <em>Microcystis </em>create toxins, including microcystins that can lead to liver damage and cancer in aquatic life, livestock and humans. Microcystins can be stored intracellularly or released into the water column in a dissolved form. Most studies focus on <em>Microcystis </em>in its …
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Purification, detection and biological effects of cyanobacterial toxins.
… of another group of cyanobacterial toxins called microcystins was also addressed. The routine monitoring of cyanobacterial cultures and natural bloom samples for microcystins relies on HPLC. However, the lack of purified standards has hindered accurate detection and quantification of many …
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Toxic cyanobacteria, cyanotoxins and drinking water production in Ghana: implications to human health
… purification and concentration of dissolved microcystins were done using the Solid Phase Extraction method. Identification of microcystins was done through comparison with commercial standards and their characteristic UV- spectra, and quantified by extrapolations of HPLC peak areas at 238 nin …
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Effects of hydrothermal liquefaction on algal toxins from harmful algae blooms
… for the seven algal toxins tested in HTLaq (microcystins RR, LR, YR, LY, LA, LW, and nodularin) when operated at 300 °C for 30 minutes, which provided an average percent removal of 98% across the seven toxins tested. Additionally, optimization of temperatures was explored to determine how …
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Part I. Metabolites From the Pohnpei Sponge Stylissa Massa. Part II. Identification of Illudin S as the Sole Antiviral Compound in the Fruiting Bodies of Omphalotus Illudens. Part III. Structure Elucidation of Oscillacidins a and B From a Homer Lake Oscillatoria Sp
… spp. we collected in hopes of isolating new microcystins, two new nonmicrocystin peptides, oscillacidins A and B, were isolated which contain the rare beta-amino acid 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid (Aound). In efforts to support the proposed structure of these two new …
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An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806.
… The effect of exogenous cyanopeptides such as microcystins, aerucyclamides, anabaenopeptins, aeruginosamide, cyanopeptolin and aeruginosin on M. aeruginosa PCC7806 was evaluated using a rapid bioassay approach along with an automated cell enumeration technique. The results indicate that at …
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Factors affecting the growth and toxin content of key cyanobacteria species in a changing world.
… that under nitrogen abundant conditions microcystins may perform an eco-physiological function, which is reduced under nitrogen deprivation and/or when cells are rapidly dividing. In the second part of the study time series monitoring of cyanobacteria taxa, toxin concentrations and a …
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Assessment of co-occurrence of cyanotoxins, toxic metals and anionic surfactants in irrigation water, agricultural soils and food crops
… kits from Merck, respectively. The levels of Microcystins (MCs), anionic surfactants, and metals were detected and quantified using the ELISA method, anionic surfactant portable photometer and inductively coupled plasma mass spectrometry (ICP- MS), respectively. The results are presented for …
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Chlorine dioxide impacts on microcystis aeruginosa cell stress, growth and microcystin production
… between ClO2 treatment and stress as well as microcystins production exist. However, no relationship was observed between stress and microcystins production. Further, low population densities exhibited a greater response to the disinfection, and had the greatest ClO2 related cyanotoxin …
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Removal of organic compounds from aquatic environments by advanced oxidation processes.
… the removal of Microcystis aeruginosa cells and microcystins. A common way of verifying the effects of light-driven treatments on cyanobacteria is by performing lab-scale experiments, where cyanobacteria are cultured in growth media. In the current study, six Microcystis aeruginosa strains …
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Microplastics as a vector for micropollutants in aquatic environments.
… of microplastics as a vector for cyanotoxins (microcystins) and anthropogenic contaminants (pharmaceuticals) in freshwater. To this end, polypropylene (PP), polyethylene (PE), polyethylene terephthalate (PET), polyamide (PA), polystyrene (PS), and polyvinyl chloride (PVC) microparticles were …
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Degradation of microcystin-LR by aquatic bacteria.
Microcystins are cyclic heptapeptide toxins produced by cyanobacteria. They are potentially a threat to human and domestic animals so are of worldwide interest. Microcystin-LR is stable in various environmental conditions. It is important to know the factors affecting microcystin degradation which …
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Reengineering and Discovery of Nonribosomal Peptide Synthetases
… penicillin and vancomycin and the deadly microcystins and cereulide. This important category of natural products is thus a focus of many research labs around the world, including the Kelleher lab. These often complex peptides are assembled by large enzymes having multiple active sites for …
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Harmful algae, algal toxin, taste and odor control and mitigation in public water system
… (cyanobacteria) to produce cyanotoxins including microcystins (MCs), mainly MC-LR, cylindrospermopsin (CYN), and taste and odor (T&O) compounds. Various types of chemicals are widely used in drinking water treatment plants as oxidants for treating source water challenged with harmful algal blooms. …
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