Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 883 for “"microbes"”.
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Gut microbes and brain function
The gut-brain-microbiota axis comprises an extensive communication network between the brain, the gut, and the microbiota residing there. If the composition or the diversity of the gut microbiota is impaired, this can have negative consequences for host health and has been associated with disorders …
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Physical ecology of marine microbes
Marine microbes play a fundamental role in driving ocean ecosystem dynamics and biogeochemistry. While their importance is global in scale, microbial processes unfold at the level of single cells and are intimately dependent on interactions between microorganisms, their neighbors, and the …
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Mining microbes to engineer novel biosensors
… biosensors which can monitor critical markers. Microbes have evolved over 3 billion years to detect and respond to virtually all classes of stimuli, yet they remain a vastly untapped and uncharacterized resource. Herein, we describe platform technologies for mining microbes to identify …
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Responses of Rumen Microbes to Excess Carbohydrate
Some species of rumen microbes respond to excess carbohydrate by synthesizing reserve carbohydrate, but others respond by spilling energy (producing heat alone). The response of mixed cultures of species, however, has not been directly studied, and elucidating the response was the focus of the …
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Signatures of gut microbes in human diseases
The human body constitutes a complex ecosystem inhabited by a vast and diverse community of microorganisms. Through evolution, host-microbe interactions have been shaped toward mutually beneficial relationships that support host health. Consequently, perturbations of the microbial compartment are …
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Iron and the ecology of marine microbes
Iron is a cofactor of a number biochemical reactions that are essential for life. In the marine environment, this micronutrient is a scarce resource that limits processes of global importance such as photosynthesis and nitrogen fixation. Given that marine microorganisms play a central role in …
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Molecular biogeochemistry of modern and ancient marine microbes
… earth today) as a model system, we explored how microbes use the limited nutrient resources available in the marine environment to make the protein catalysts that enable primary production. Quantification of the Prochlorococcus proteome over the diel cell-division cycle reveals that protein …
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Analysis of Behavior in Populations of Swimming Microbes
<p>This work describes our work developing an experimental biological system to study patterns of behavioral variability. We selected motility as the behavior of interest because it is common throughout biology and can be recorded and analyzed relatively easily. We chose to work with a microbe, …
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Predicting Colonization of Microbes in the Human Gut
<p>The human gut is home to trillions of microbes that interact intimately with the host and its diet. An important emergent phenotype by these microbes is colonization resistance, the process by which a microbial community resists colonization of an exogenous microbe. This resistance barrier is …
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Antimicrobial activities and diversity of sponge derived microbes
In this study, marine sponges collected in Irish waters were analysed for their associated microbiota. Of the approximately 240 bacterial isolates obtained from two sponges several showed antimicrobial activity; among them members of genera which have rarely been shown to produce antimicrobial …
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Molecular Biogeochemistry of modern and ancient marine microbes
… earth today) as a model system, we explored how microbes use the limited nutrient resources available in the marine environment to make the protein catalysts that enable primary production. Quantification of the Prochlorococcus proteome over the diel cell-division cycle reveals that protein …
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Fine-scale ecological dynamics of closely related marine microbes
… spatiotemporal scales, and even closely related microbes are known to vary in their ecological distributions, most work has characterized dynamics at bulk scales and with low genetic resolution. Thus, little is known about the effects of finer structure. In this thesis, I show that characterizing …
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Investigation of the Interactions Among Grass, Chlorophenols and Microbes
… phenols. The lag time for acclimation of microbes to TCP mineralization was affected by the ratio of the alternate organic carbon source concentration to the biomass concentration. It is proposed that the presence of a readily available, alternate organic carbon source affected lag time …
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Characterizing cobalamin cycling by Antarctic marine microbes across multiple scales
… low B12, which is also found in other marine microbes. Across Antarctic seas, community-scale cobalt and B12 uptake rates were measured by 57Co radiotracer incubation experiments and integrated with hydrographic and phytoplankton pigment data. I observed significant correlations between uptake …
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Isolation and Identification of Biphenyl and Polychlorinated Biphenyl Degrading Microbes
The San Jacinto River system south of the I-10 overpass is heavily contaminated with biphenyl and polychlorinated biphenyls (PCBs), carcinogenic aromatic hydrocarbons that have a deleterious impact on the environment. While typically recalcitrant to most forms of environmental degradation, biphenyl …
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Ecological and evolutionary aspects of interactions between microbes coinfecting plants
Coinfections of one host with multiple pathogen species are common, and have important implications for host health and pathogen fitness. In the research reported here, plant virus systems were used to explore the effects of coinfection on pathogen populations and host responses. Chapter 1 …
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Colonization dynamics of oro-gastrointestinal microbes critical to infant health
… in the gastrointestinal tract by other microbes. Several commensal microbes are strongly glycolytic and liberate mono- and disaccharides from fermentable fibers and the gastrointestinal mucin layer. These liberated carbohydrates are available for any microorganisms capable of …
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Gut microbes and serum metabolomics in canine with diabetes mellitus
Enteric microbial dysbiosis contributes to the pathobiology of canine diabetes mellitus (DM) in several ways, including interference with the host metabolism, promotion of inflammation, and altered incretin hormone responses. Enriching and diversifying an unbalanced gastrointestinal (GI) microbiome …
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Semi-biological domino catalysis using acetate- and propionate-producing microbes
Acetic acid and propionic acid are industrially relevant feedstock chemicals with applications in the production of polymers and food additives. The current production routes for both acetic acid and propionic acid in the chemical industry predominantly rely on fossil raw materials or …
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Characterizing cobalamin cycling by Antarctic marine microbes across multiple scales
Highly productive marine microbial communities in the coastal Southern Ocean sustain the broader Antarctic ecosystem and play a key role in Earth's climate via the biological pump. Regional phytoplankton growth is primarily limited by iron and co-limited by cobalamin (vitamin B₁₂), a trace …
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