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Showing 1 to 1 of 1 for “"microRNA-33"”.

  1. The APOE Pathway as a Modulator of Amyloid Pathology in Alzheimer's Disease Models

    … the importance of lipid homeostasis in AD. MicroRNA-33 regulates the expression of ABCA1 and apoE lipidation, although its effect on amyloid pathology is unknown. Additionally, apoE variants can modulate AD risk. The apoEε4R251G variant eliminates the increased risk associated with the …

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