Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"microRNA-155"”.
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Role of AID and microRNA-155 in c-myc-IgH Translocations
… IL6. We also investigated the potential role of microRNAs (miRNAs) in AID mediated processes. MiRNAs are small non-coding RNAs that regulate vast networks of genes that share miRNA target sequences. To examine the physiologic effects of an individual miRNA in vivo we created a knock-in mouse that …
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Role of microRNA-155 in dendritic cells and macrophages: MiR-155 directly targets PU.1 and IL13Rα1
… or pro-tolerogenic) macrophages, BIC (microRNA 155 hosting gene) was found up regulated under inflammatory conditions. MicroRNAs are non coding RNAs of ~22nt in length that inhibit gene expression upon pairing to the 3’UTR (UnTranslated Region) of target mRNAs. <i>In silico </i>analysis …
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Algorithms And Tools For Computational Analysis Of Human Transcriptome Using Rna-Seq
… We have employed RAEM to predict isoform-level microRNA-155 targets. The second is called dSpliceType, which is a read coverage-based algorithm and tool to detect differential splicing events. It utilizes sequential dependency of normalized base-wise read coverage signals and a change-point …
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MicroRNA as Regulator of the Th17 Inflammation in Behcet's disease
BACKGROUND: MicroRNAs (miRNAs) play a critical role in the regulation of host genomic expression; they are also involved in regulation of the immune response by control of target genes. Recent studies of miRNAs have revealed that aberrant expression and/or function of miRNAs in chronic inflammatory …