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Showing 1 to 6 of 6 for “"micro-total analysis system"”.
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Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection
<p>The emerging field of micro total analysis system powered by microfluidics is expected to revolutionize miniaturization and automation for point-of-care-testing systems which require quick, efficient and reproducible results. In the present study, a PDMS based micro total analysis system has …
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Modeling, simulation, and fabrication of a PZT valveless micropump
<p>A micropump is one of the most important elements in a micro-total analysis system used for rapid chemical and biological analysis. To date, different kinds of micropumps have been designed, fabricated, tested, and implemented. Among them, a PZT valveless micropump is receiving increasing …
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Microfabrication and Evaluation of Planar Thin-Film Microfluidic Devices
Over the past 15 years, research in the field of microfluidics has rapidly gained popularity. By seeking to miniaturize and automate separation-based analysis, microfluidic research seeks to improve current methods through decreased cost, analysis time, and sources of contamination. My work has …
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Two-Dimensional and High-Throughput Electrophoretic Separation of Proteins Using Polymeric Microchips
… digestion of the proteins. For 2-D separations, microfluidic devices are superior to bench top and capillary-based systems since they potentially provide higher separation efficiencies due to the minimal dead volumes produced during peak transfer between the two separation dimensions. In …
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Integrating Micro-Scale Separations to Matrix Assisted Laser Desorption and Ioniation Time of Flight Mass Spectrometry (MALDI-TOF-MS) for Protein Analysis
This dissertation describes the integration of micro-scale separations to matrix assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI TOF MS) for protein analysis. MALDI MS provides unsurpassed accurate mass measurements of intact bio-molecules, for example peptides and …
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Rational Design and Advanced Fabrication of Metallic Nanostructures for Surface-Enhanced Raman Spectroscopy
… gold nanostructures optimized to probe molecular systems, at the monolayer level in a variety of configurations, is described. Using advanced nanofabrication techniques, two-dimensional arrays of metallic nanostructures were inscribed onto glass slides. The fabricated SERS platforms were first …