Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"miR-9"”.
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miRNA expressione profiles in retinal neurodegenerative diseases
I micro RNA (miRNAs) sono piccole molecole di RNA non codificative che regolano l'espressione genica a livello post-trascrizionale e post-trasduzionale. Diversi studi dimostrano che i microRNA regolano diversi processi cellulari tra cui differenziazione, crescita, invecchiamento, apoptosi, …
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Visualization and manipulation of microRNA in neural cells
microRNA (miRNA) are small non-coding RNA, 21-23 nucleotides long. miRNA provide a new layer of regulatory control over gene expression programs. It is increasingly evident that miRNA are cell type and tissue specific. Many miRNAs have been identified to be highly abundant in certain regions of the …
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MicroRNAs en tejido de cordón umbilical y su relación con el peso al nacimiento
… complications. In this context, microRNAs (miRNAs), essential epigenetic regulators of gene expression at the post-transcriptional level, may play a crucial role in birth weight alterations. The main objective of this study was to analyze the relationship between miRNA expression in …
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Identification de microarns circulants comme biomarqueurs à potentiel diagnostique de la sclérose latérale amuotrophique
… à la SLA ont été observés incluant le miR-9-5p, miR-183-5p, miR-338-3p et miR-1246. Les miARNs miR-15a-5p et miR-193a-5p ont également été notés pour leur potentiel à diagnostiquer la SLA et à discriminer les patients à divers stades de la maladie, respectivement. De plus, les …
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Peripubertal Binge Ethanol, Age and Sex Modulate Microrna Expression in the Ventral and Dorsal Hippocampus of the Adolescent Rat
… expression profiles of EtOH-sensitive microRNAs (miR-10a-5p, miR-26a, miR-32, miR-103 and miR-495), E<sub>2</sub>-responsive microRNAs (miR-7a, miR-9, miR-125a and miR-181a), BDNF, SIRT1, Drosha and Dicer are differentially dependent on sex and age throughout pubertal development. This research …
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THE ROLE OF P2X7R IN METHAMPHETAMINE-INDUCED BEHAVIORAL CHANGES AND MICROGLIAL EFFECTOR FUNCTIONS
… or microvesicles, and contain protein, mRNA and miRNA that alter the biological activity of target cells. I used electron microscopy, nanosight quantification, and confocal imaging techniques to confirm that METH causes the increase in primary human microglia-derived exosomes, which are around …
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EMISSIVE PEPTIDE NUCLEIC ACIDS (PNAS): POTENTIAL TOOLS FOR INNOVATIVE DIAGNOSTICS AND THERAPEUTICS
… realize the objectives of the project. VI. Anti-miR124 PNAs for in vivo studies in ascidian embryos Besides the work on emissive PNAs, a part of this Ph.D. thesis was also dedicated to the study of anti-miR124 PNAs for in vivo studies using ascidian embryos as animal model. Anti-miR PNAs have …