Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"miR-483"”.
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Effects of 5-fluorouracil Drug Treatment on the Expression Profile of MicroRNAs in MCF7 Breast Cancer Cells
… 5-FU treatment. We hypothesized that microRNAs (miRNAs), the newly identified class of small regulatory RNAs, might play a mediator role in inducing the cytotoxicity of 5-FU, by regulating the expression of its target genes. Using a combined advanced microarray and quantitative real time PCR …
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Immunogenetic regulation of Natural Killer cell function in pregnancy
… due to reduced expression by human uNK cells of miR-483-3p, which stimulates endogenous insulin-like growth factor (IGF)-1 production and uNK cell cytotoxicity in vitro. It is demonstrated here that neither miR-483-3p nor IGF-1 regulate murine NK cell development, maturation or function. No …
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Extracellular Metabolic Energetics Can Promote Cancer Progression
… describes the identification of two microRNAs, miR- 483-5p and miR-551a as suppressors of liver metastasis by human colon cancer cells using two parallel, complementary xenograft models of colon cancer metastasis. The first approach involved a functional library-based in vivo screen of 661 …
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Anotación de nuevos microRNAs en el genoma porcino mediante una aproximación basada en Machine Learning
La predicción computacional de microRNAs (miRNAs) supone un campo de investigación activo en la actualidad, sobre todo en especies no modelo cuyas anotaciones son aún limitadas y poco fiables. Mediante la utilización de una aproximación basada en algoritmos de Machine Learning como el Support …
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Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer
… observed that the expression of the microRNA (miRNA) miR-92a could provide independent prognostic information in breast cancer patients, and loss of miR-92a was associated with more severe breast cancer traits. The earliest histologically identifiable breast lesion with an increased risk for …
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ALTERAZIONE DEL miRNoma INTRACELLULARE ED EXTRACELLULARE ED ANALISI BIOINFORMATICA IN MODELLI IN VITRO DI NAFLD E DI NASH
… validato la deregolazione dei seguenti microRNA: miR-126, miR-150, miR-223, miR-483-3p, miR-1226*, miR-1290. Utilizzando un nuovo approccio computazionale per l'analisi della perturbazione delle pathway, abbiamo riscontrato che i target dei microRNA intracellulari ed extracellulari erano coinvolti …