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Showing 1 to 2 of 2 for “"miR-301"”.

  1. Microrna Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development

    … therapeutics. Recent discoveries of microRNA (miRNA) have provided a new avenue in understanding the regulatory mechanisms of cancer. However, how miRNAs may regulate CSCs is still poorly understood. Here, we present miRNA expression profiling in six populations of prostate cancer (PCa) …

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  2. E2F1 and Tumor Suppression: The Role of P21, Mirnas, and The Dna Damage Response

    … suppressive properties: p21-induced senescence, miRNAs, and the DNA damage response. We found that E2F1 acts as a tumor suppressor in response to ras activation through a non-apoptotic mechanism requiring ARF and p53, but not p21. However, p21-loss inhibited two-stage chemical carcinogenesis in …

    uthsc Repository record for E2F1 and Tumor Suppression: The Role of P21, Mirnas, and The Dna Damage Response (opens in a new tab)