Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"miR-214"”.
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Antagonistic Roles of miR-199a-3p/miR-214 and the miR-200 Family in the Regulation of Uterine Contractility During Pregnancy and Labor
… understood. Recently, we discovered that miR-200 family members, miR-200b and miR-429, and their target, transcription factor ZEB1, serve as P4/progesterone receptor (PR)-mediated regulators of uterine quiescence during pregnancy (Renthal et al., 2010). In the present study, we identified …
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Investigation of regulatory functions of micrornas in skin and hair follicle development and cycling. A role of microRNA-214 in skin and hair follicle homeostasis.
miRNAs are important post-transcriptional regulators of gene expression which play vital roles in the arrays of physiological processes, including skin and hair follicle (HF) development. In this study, the role for miR-214 in the skin and HF development and their postnatal physiological …
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Role of microRNA 214 in cyclic stretch induced aortic valve pathogenesis
… this disease. In this regard, mechanosensitive miRNAs have been considered as potential therapeutic candidates for CAVD, due to their role in modulating gene expression. microRNA 214 (miR-214) is a major miRNA which is significantly downregulated in calcified aortic valves (AVs). Previously, …
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Exploring Molecular Mechanisms Controlling Skin Homeostasis and Hair Growth. MicroRNAs in Hair-cycle-Dependent Gene Regulation, Hair Growth and Associated Tissue Remodelling.
… of gene activation and silencing. MicroRNAs (miRNAs) are critically important for gene silencing and delineating their role in hair cycle may provide new insights into mechanisms of hair growth control and epithelial tissue remodelling. The aims of this study were: 1) To define changes in the …
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Biomarkers for Personalised Treatment Approach in Patients with Multiple Myeloma // Биомаркери за персонализиран подход при подбора на лечение при пациенти с миеломна болест
… to evaluate the role of circulating microRNAs (miRs) as diagnostic and prognostic biomarkers in multiple myeloma (MM). The cohort includes 56 untreated MM patients and 12 healthy controls, with a focus on the quantitative determination of expression levels of five selected miRs: miR-199a-5p, …