Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"methylome-wide association studies"”.
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Integrative Approaches in Genomic Analysis: Advancing Epigenetic Prediction, Twas Methodology, and Cell-Type Deconvolution in Spatial Transcriptomics
… blocks of life. Conventional observational studies grapple with major limitations in exploring the relationships between diseases and gene expression, leading to the advent of transcriptome-wide association studies (TWAS). Similarly, methylome-wide association studies (MWAS) have been …
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Understanding and stratifying brain health through blood-based omics data
… The first aim of this thesis is to perform methylome-wide association studies (MWAS) of circulating proteins, with a focus on those related to brain health. DNAm patterns can also be used to derive proxy scores for protein levels – an approach that is somewhat analogous to polygenic scores. …