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Showing 1 to 1 of 1 for “"methylisocitrate cycle"”.
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Structure-Based Drug Design Against a Biosecurity Pathogen
… this challenge from two directions. Firstly, 2-methylisocitrate lyase is identified as a potential target for a new C. burnetii inhibitor, including the first substrate bound structure. X-ray crystallography-based fragment screening is then applied, identifying a large number of binding …