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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 54 for “"methylcellulose"”.
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Elucidating Dual Methylcellulose-and-Oil-Nanoemulsion Thermoresponsive Gelation
… hydrogel-colloidal gel system composed of a methylcellulose-stabilized oil nanoemulsion. This system has tunable rheology with two distinct dominant load-bearing components. Oil volume fraction determines which component leads to elasticity in the gel network. At low oil volume fraction, …
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Development of an Injectable Methylcellulose Hydrogel System for Nucleus Pulposus Repair and Regeneration
… hydrogel system for NP replacement and repair. Methylcellulose (MC) is cellulose derivative that forms physically crosslinked gels at increasing temperatures. Methacrylation of MC allows for the formation of more robust, chemically crosslinked hydrogels with lower effective macromer …
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Development and characterization of edible films made from four dietary fibers -pectin, guar gum, locust bean gum, and hydroxypropyl methylcellulose
… gum, locust bean gum, pectin, and hydroxypropyl methylcellulose, and glycerol concentration to the mechanical properties and dissolution/ partial dissolution time of their films and the viscosity of their solution. Specifically, it investigates if the higher glycerol and polymer concentration …
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Effect of Antibiotic Pastes on Chemical Structure and Microhardness of Radicular Dentin
… The 1 g/mL of TAP or MTAP and the 1 mg/mL methylcellulose-based TAP caused significant reduction in microhardness of roots compared with untreated control roots at 500 µm and 1000 µm from the pulp-dentin interface. Furthermore, the methylcellulose-based 1 mg/mL TAP and MTAP caused …
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Biological control studies of Phytophthora Parasitica root rot of boxwood using multiple antagonists
… two polymers, carboxymethyl cellulose (CMC) and methylcellulose (MC) for their suitability as carriers, storage media, and carbon substrates; and finally to determine the efficacy of selected antagonist pairs in controlling Phytophthora root rot on containerized American boxwood. On the basis of …
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Amorphous calcium phosphate nanocomplexes in dental film formulations
… of 2% w/v E10M and 1% w/v F4M hydroxy propyl methylcellulose, loaded with 2 % w/v 4 hours acidic hydrolysed carboxy methylcellulose and hydrolysed casein, had a suitable release of calcium. The release pattern of the calcium was characterised using different diffusion/erosion models and was …
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Physicochemical and tableting properties of crystallised and spray-dried phenylbutazone containing polymeric additives. Effect of polymeric additives (hydroxypropyl methylcellulose and a polyoxyethylene-polyoxypropylene glycol) on the crystalline structure, physicochemical properties and tableting behaviour of crystallised and spray-dried phenylbutazone powders
… of two hydrophilic polymers - hydroxypropyl methylcellulose (H. P. M. C. ) and the surfactant poloxamer 188 - prepared by both conventional crystallisation and spray drying are reported. As an integral nart of the work attempts were mado to identify the different polymorphic forms of …
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The enzymatic solubilization of crystalline cellulose
… was several times more inhibitory than glucose. Methylcellulose was very inhibitory. Sulfhydryl compounds stimulated activity of the crude preparation. EDTA was without effect.
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Grewia polysaccharide gum as a pharmaceutical excipient
… may be preferable to gum Arabic or sodium carboxymethylcellulose as a suspending agent in ibuprofen suspension formulations. The release retardant property of the gum was superior to guar and Metolose® in ibuprofen matrices. Similarly, carboxy methylcellulose, Methocel®, gum Arabic or Metolose® …
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Nanoemulsion-Loaded Hydrogels For Advanced Pharmaceutical Formulations
… cores. Second, we design a new thermogelling methylcellulose (MC) nanoemulsion that can be efficiently formulated into composite solid dosage drug products with well-controlled API nanocrystals embedded in a MC matrix. The composite drug products possess a fast and tunable release performance …
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A Study of HPMC-PEG Matrix as Drug Carrier in Spray Congealing
… of the additives showed that hydroxypropyl methylcellulose (HPMC) was an appropriate matrix modifier for PEG. The impact of grade and concentration of HPMC on the physicochemical properties of the molten mixtures, drug (metronidazole), PEG matrix and spray congealed microparticles was …
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Formulation and characterisation of novel films for buccal mucosa drug delivery for paediatric patients
… different film forming polymers hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), sodium alginate (SA), carrageenan (CA) and metolose (MET) were used initially and subsequently with polyethylene glycol (PEG 400) as plasticiser and L-arg (to stabilise OME). Polymeric gels (1% w/w) were …
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Investigation of key non-coding and coding genes in cutaneous melanomagenesis
… cells inhibited colony forming ability in methylcellulose, an in vitro surrogate assay for tumourigenicity. Moreover, elevation of miR-200c resulted in increased expression levels of E-cadherin through negative regulation of the zinc finger E-box-binding homeobox 2 (ZEB2) gene. Ectopic …
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Development of an Adhesive Emulsion Hydrogel for Soft Tissue Reconstruction
… of food, cosmetic, and biomedical products. Methylcellulose (MC), an amphiphilic cellulose derivative, may be methacrylated to produce injectable, redox-polymerized hydrogels that can form covalently bonded, long-lasting soft implants in situ. Carboxymethylcellulose can be oxidized via …
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Clarithromycin nanocrystals for high-dose inhalation
… good flow and dispersion. Hydroxypropyl methylcellulose (HPMC) served as a dual-function excipient, stabilising nanocrystals during milling and acting as the spray-drying matrix, enabling low excipient load. Adding a citric acid/NaOH buffer (pH 5) markedly improved nanocrystal …
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Measurement, optimisation and control of particle properties in pharmaceutical manufacturing processes
… particles using D-mannitol and hydroxypropyl methylcellulosewithin a selected, pragmatic particle design space. The results indicate a significant impact ofhydroxypropyl methylcellulose reducing liquid evaporation rates and particle drying kinetics.The morphology and internal structure of the …
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Apical and radial pH diffusion through root dentin from five modern intracanal medicaments: a twelve-week evaluation of alkaline dynamics
… groups: purified water, propylene glycol, methylcellulose in water, silicone oil, or calcium silicate. Standardized cavities were prepared at inner dentin, outer dentin, and two apical sites approximately 3 mm and 6 mm beyond the medicament terminus. Remaining dentin thickness between the …
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Direct Single Molecule Imaging of Enhanced Diffusion for Enzymes and Enzyme-conjugated Dna origami
… coated surface) and different viscosity agents (methylcellulose and glycerol) to slow diffusion and facilitate tracking. We found that high amounts of glycerol inhibited enzyme activity, resulting in the failure to observe the enhanced diffusion. To get rid of glycerol, we tethered enzymes …
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Production of stable bcs class ii drug suspensions by melt emulsification and subsequent incorporation into polymer strip films
… suspension is blended with hydroxypropyl methylcellulose film solution and cast into a solid strip film by oven drying. The film is characterized by redispersion and by dissolution rate. Particles are recovered from the films in de-ionized water within 5 minutes with no size increase, and …
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