Global ETD Search
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Showing 1 to 4 of 4 for “"methionine salvage"”.
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Purification and Characterization of 5'-Methylthioadenosine Nucleosidase From Avocado and Tomato
… were also assessed. Results suggested that the methionine salvage pathway in non-ripening mutant tomatoes was also active but at a reduced rate.
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Methanocaldococcus jannaschii and the Recycling of S-adenosyl-L-methionine
S-Adenosyl-L-methionine (SAM) is an essential metabolite for all domains of life. SAM- dependent reactions result in three major metabolites: S-adenosyl-L-homocysteine (SAH), methylthioadenosine (MTA), and 5'-deoxyadenosine (5'-dA). Each of these has been demonstrated to be feedback inhibitors of …
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Synthesis And Characterization Of Nickel Complexes With Relevance To Nickel Acireductone Dioxygenase And Nickel Superoxide Dismutase
… (ARDs) are a unique set of enzymes found in the methionine salvage pathway that catalyze the oxidation reaction of acireductone (1, 2-dihydroxy-3-oxo-5-(methylthio)pent-1-ene). These enzymes share a compolypeptide sequence but bind different metal ions, Ni2+ or Fe2+, at the active site. The …
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Therapeutic Potential of Prmt5 and Mat2A As Synthetic Lethal Targets In Mtap-Deficient Gbm Tumors
… MTAP is a critical metabolic enzyme in the methionine salvage pathway responsible for the breakdown of methylthioadenosine (MTA). As a result, <em>MTAP</em>-deleted cells cannot metabolize MTA, leading to the accumulation of MTA. High levels of MTA in <em>MTAP</em>-deleted cells partially …