Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"methionine cycle"”.
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THE METHIONINE CYCLE AS A NOVEL THERAPEUTIC TARGET IN NPM1C DRIVEN ACUTE MYELOID LEUKEMIA
… Fibroblasts (MEFs) leads to an unbalanced methionine-cycle with decreased ratio between S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH), key metabolites of the methionine cycle. Decreased SAM/SAH ratio is known to inhibit cellular methyltransferases activity. Consistently, the …
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The Redox and Systems Biology of Ergothioneine Biosynthesis in Aspergillus fumigatus
… in ΔvipC. Additionally, enzymes involved in the methionine cycle also had decreased abundance. These data indicate that VipC plays a significant role in coordinating the metabolic response to EGT absence in A. fumigatus. As a sulphur-containing metabolite, EGT therefore plays a key role in redox …
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Investigating and exploiting fungal natural products in Aspergillus spp.
… especially metabolism. Two putative S-adenosylmethionine (SAM)-dependent methyltransferases showed de novo abundance under GT conditions. In addition an increase in abundance of proteins involved in the methionine cycle was also observed. Analysis of methionine-related metabolites revealed …
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Investigating the genomic, transcriptomic and metabolic landscape of Chlamydomonas reinhardtii in the context of vitamin B12 availability
… the global transcriptomic and one- carbon cycle related metabolite alterations in response to vitamin B12 scarcity in a B12 auxotroph and its B12-independent progenitor of C. reinhardtii and characterise common strategies eukaryotic cells use to cope with low B12. Findings highlight that …