Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 35 for “"metazoa"”.
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Characterization of D-amino acid-containing neuropeptides from metazoa
… peptides (DAACPs) have been discovered in metazoan species since the early 1980s. Hormones, antimicrobial peptides and toxins have been found in this list; and in several cases, neuropeptides, a group of cell-to-cell signaling molecules found in the neural tissues, were also shown to …
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Molecular Evolution in non-bilaterian Metazoa with Emphasis on Phylum Porifera
… Beziehungen der basalen Stämme innerhalb der Metazoa (Porifera, Placozoa, Cnidaria and Ctenophora) sind noch immer nicht abschliessend geklärt und Gegenstand wissenschaftlicher Diskussionen. Ein Grund für unser fehlendes Verständnis ist die einfache Organisation dieser Tiere, die nur wenige …
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Methodological advances for the measurement of the D-amino acids across the metazoa: From mollusks to man
The amino acids are a class of biomolecules which is obligatory to terrestrial life, alongside nucleic acids, fatty acids and monosaccharides. The amino acids, with the exception of glycine, are chiral molecules which exist as either L- or D-amino acids. Although identical with regard to physical …
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Evolution of Sp Transcription Factors in Metazoans
… sequenzierte Genome verschiedener Vertreter der Metazoa nach Sp Genen durchsucht. Phylogenetische Analysen dieser Daten, s! owie Proteindomänenanalysen, chromosomale Lokalisation und mRNA Expressionsanalysen zeigten, dass btd Orthologe schon in so basalen Metazoa wie Nematostella vectensis und …
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Bridging the gap between microbial and metazoan evolutionary history
… microbial fossils and biomarkers. Conversely, metazoans (animals) emerged relatively recently and have deposited a thorough archive of their existence in the rock record. The ancient shared ancestry of these two groups presents an opportunity to leverage the rich metazoan fossil record to …
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Comparative genomics of early animal evolution
… into the origin and early evolution of the Metazoa at the molecular level. In this thesis, I am particularly interested in investigating the molecular foundation of the animal senses (i.e. how animals perceive their world). To understand the directionality of evolutionary innovation a …
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A STUDY OF THE MICROORGANISMS INHABITING ROTATING BIOLOGICAL CONTACTOR BIOFILMS DURING VARIOUS OPERATING CONDITIONS
… interrelationships among bacteria, protozoa, and metazoa and their perceived environment. Since very little information is available on the microorganisms inhabiting the biofilms, the major objective of this research was to increase the understanding of the biological interactions occurring in RBC …
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Genetic Dissection of DH31 Signaling in Drosophila
… in mediating stress behaviors throughout the Metazoa.
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Alternative Splicing Expands Spatiotemporal Expression Complexity of Arthropod N -Cadherin
Metazoan development requires mechanisms to generate cells with diverse functions. Cellular diversity is dictated by complex patterns of molecular expression, originating from dynamic spatiotemporal regulation of transcriptomes. Both gene duplication and alternative splicing have been proposed as a …
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Characterization of split ends function during Drosophila eye development
… transduction pathways coordinate all aspects of metazoan development, including cell fate specification, differentiation, and growth. Rather than functioning as completely independent modules, signaling pathways interface to create a web of specific interactions that a cell integrates in a …
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Neuropeptidomics Across Metazoan Life
… neurochemical pathways are well conserved across metazoa, and thus working with simpler model organisms can provide valuable insights into the fundamental principles in the human brain. Several animal models have been commonly used in neuroscience studies, with each having specific advantages for …
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Genetic encoding of a stable <i>O</i>-GlcNAc analogue
… event in mammals and most other metazoa, catalysed by a unique <i>O</i>-GlcNAc transferase (OGT) and removed by an <i>O</i>-GlcNAc hydrolase (OGA). Despite the existence of a single writer/eraser pair, proteomic studies have identified over 4000 O-GlcNAcylated proteins in the …
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Mitochondrial Genomics: structure, inheritance and phylogenetic utility of the Mitochondrial genome in Bivalvia and Insecta
… different taxonomic levels in different taxa of Metazoa. From a methodological standpoint, my main effort was dedicated to the sequencing of complete mitochondrial genomes, and the approach to whole-genome sequencing was based on the application of Long-PCR and shotgun sequences. Moreover, this …
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Molecular phylogenetics of the Metazoan clade Lophotrochozoa
… relationships between taxa within the metazoan clade Lophotrochozoa. Chapter 1 presents an introduction to phylogenetics of the Metazoa and the clade Lophotrochozoa. Chapter 2 analyzes higher level relationships between the major groups within the phylum Mollusca using sequences of the …
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Developing and applying supertree methods in Phylogenomics and Macroevolution
… a variety of datasets (i.e. the datasets for the Metazoa and the Carnivora), and I have also recovered the first Bayesian supertree-‐based phylogeny of the Eubacteria and the Archaebacteria. These new SMs are discussed, with reference to other, well-‐ known SMs like Matrix Representation with …
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Genetic analysis of endoplasmic reticulum homeostasis during stress and infection of Caenorhabditis elegans
… and organismal homeostasis, eukaryota and metazoa rely on conserved, integrated stress response pathways. Throughout its life cycle, the free-living nematode Caenorhabditis elegans encounters diverse microbial taxa, including both nutritional and pathogenic species. Intestinal infection …
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Developing O-GlcNAc transferase inhibitors - insights from substrate recognition
… is a highly dynamic and essential process in metazoa. The attachment and removal of the sugar residue is regulated by two antagonistic enzymes. The O-GlcNAc transferase (OGT), which adds the sugar onto protein substrates and the O-GlcNAc hydrolase (OGA), which removes it. Mass spectrometric …
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Reversible Germline Dynamics of Caenorhabditis elegans During Exposure to Pathogenic Bacteria
… affects reproductive fitness and fecundity in metazoa. Caenorhabditis elegans is a free-living nematode and well-characterized animal model that encounters pathogenic microbes in its natural environment. How these pathogens affect the reproductive capacity of C. elegans is not well understood. …
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Next generation sequencing technology and phylogenomics enhance the resolution of deep node phylogenies: A study of the Protostomia
… findings of a Cryogenian origination for the Metazoa and a Lower Cambrian radiation of animal lineages. The arachnids were the last of the terrestrial arthropods to colonize land in the Upper Ordovician (450 MYA), with the hexapods colonizing land in the Lower Ordovician (483 MYA) broadly in …
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Regulation Of Transcription By RNA Polymerase II In <i>S. pombe</i>
… an RNA polymerase II elongation factor that in metazoa can assemble into a larger assembly that also includes P-TEFb and other proteins encoded by genes involved in MLL translocations. This larger assembly, sometimes called SEC, binds to a specific "docking site" in the metazoan Mediator …
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