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Showing 1 to 1 of 1 for “"metastatic melanoma, proteomics, metabolomics, metabolic adaptation, membrane protease"”.
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MULTI-OMICS PROFILING DECODES BACE2-DEPENDENT METABOLIC REWIRING IN METASTATIC MELANOMA
… our group recently demonstrated that, in metastatic melanoma, BACE2 activity is deregulated and amyloid-like fibrils are secreted, altering tumor microenvironment stiffness and promoting invasive features. While investigating BACE2 role in cancer, we identified a deregulation of …