Global ETD Search
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Showing 1 to 1 of 1 for “"metaphase congression"”.
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Investigating the mitotic roles of Topoisomerase 2 Alpha and Topoisomerase 2 Beta-Binding Protein 1 in the maintenance of chromosome structure and genome stability
… thesis, I focus on the role of TOP2 in orderly metaphase congression and the maintenance of chromosome compaction during prometaphase-metaphase. These studies have been undertaken in human tumour-derived cell lines using both chemical inhibition and depletion (through siRNA and genetically …