Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"metainference"”.
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Small Molecule Binding to Disordered Proteins
… ensemble determination techniques (metadynamic metainference) to characterise small molecule interactions with disordered proteins. After an introduction to the field in Chapter 1, I focus on the interaction of a drug-like molecule with a peptide from an oncogenic transcription factor, c-Myc, in …
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INTEGRATIVE MODELLING FOR THE CHARACTERISATION OF THE STRUCTURE AND DYNAMICS OF BIOMOLECULES
… be coupled with restraining strategies, such as metainference, to generate conformational ensembles at atomistic resolution in agreement with the experimental data using MD simulations. This approach was used to determine the closed state conformations of the human gelsolin, a plasma protein. The …
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The influence of leadership development approaches on social capital: A mixed methods study
… independently, and mixed at the conclusions and metainference stage. The findings indicate that participation in an agricultural leadership program influences the social capital capacity of graduates by providing opportunities that facilitate the emergence of new, appropriable social networks. …
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Υπολογιστική ανίχνευση αναστολέων της προβληματικής αναδίπλωσης και συσσωμάτωσης των πρωτεϊνών Tau και Huntingtin που εμπλέκονται στις νευροεκφυλιστικές νόσους Alzheimer και Huntington.
… μεταδυναμικής συζευγμένης με AlphaFold-Metainference. Για την πρωτεΐνη Tau, αξιοποιήθηκε το δομικό σύνολο της ισομορφής 2N_4R προσδιορισμένο, από τους Brotzakis et. al [1], δεδομένης της ευρείας χρήσης της συγκεκριμένης ισομορφής ως πρότυπο σε πειραματικές μελέτες. Για τον καθορισμό των …