Global ETD Search
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Showing 1 to 5 of 5 for “"metagenomic assembly"”.
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Microbial profiling using metagenomic assembly
… strategies should allow the relation of metagenomic sequence data to our understanding of microbial taxonomy, while also facilitating the discovery of novel taxa. For eukaryotes, a method has been established that links DNA sequences to the identification of organisms: DNA Barcoding. A …
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Untangling Genomes from Metagenomes
… must first be brought into laboratory culture. Metagenomics has developed as an alternative approach, revealing genetic information about entire microbial communities at once. With rapid technological improvements placing metagenome-scale DNA sequencing within reach of individual researchers, …
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A phylogenetic framework for large-scale analysis of microbial communities
… and viruses present in and on the human body. Metagenomics is the most recent and advanced tool that allows the study of the microbiome at high resolution by sequencing the whole genetic content of a biological sample. The computational side of the metagenomic pipeline is recognized as the most …
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De Novo Assembly of Genomes in Microbiomes: From Amplicons to Whole-Genome Shotgun Sequencing
… sequencing technologies has greatly propelled metagenomics research. However, a critical bottleneck in current bioinformatics investigations is the assembly of metagenome at the strain-level resolution. This is indispensable for gaining profound insights into microbial communities and …
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Large-scale metagenomic analysis of food-associated microbial communities and their links with the human microbiome
… newly sequenced food metagenomes. Through an assembly-based pipeline, I reconstructed >10,000 metagenome-assembled genomes (MAGs) that resulted in 290 previously undescribed taxa and, hence, firstly observed in this work. I characterized the composition of microbial communities in food, …