Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"metabolic syndromes"”.
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Impact of saskatoon berry powder on metabolism and gut microbiota in diet-induced insulin resistant mice
… diabetes is one of the most common and prevalent metabolic disorders with an ever-increasing rate globally. Metabolic syndromes are characterized by low-grade inflammation and insulin resistance, and are usually accompanied with alteration in the gut microbiota profile. Evidence in recent decades …
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Engineering the human gut microbiome through personalized dietary interventions
… dynamic microbial community. The composition and metabolic output of the human gut microbiota have been implicated in many diseases: from inflammatory bowel disease, colorectal cancer, and diarrheal diseases to metabolic syndromes like diabetes. Treatment of these diseases will likely require …
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Comparative Effectiveness of Smoking Cessation Medications among Schizophrenic Smokers
… 47.59%) developed one or more criteria of the metabolic syndromes within just one year after the treatment. We found that smokers who were prescribed NRT were less likely to develop metabolic syndromes as compared to those who were prescribed Varenicline. Rates of suicide ideations/behaviors …
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Childhood Obesity and School-Based Interventions: An Evidence-Based Best Practice Guideline
… glucose intolerance, dyslipidemia, hypertension, metabolic syndromes, fatty liver disease, menstrual abnormalities, gallstones, sleep apnea, poor body image, low self esteem, and discrimination are all potential consequences of childhood obesity. Research indicates that school-based interventions …
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Developing C. elegans as a model to study Type 2 Diabetes Mellitus
… it is an ideal organism to study heterogeneous metabolic syndromes such as Type 2 Diabetes Mellitus (T2DM) as C. elegans can be used to delineate molecular pathways that are at the core of its problems. A growing number of populations worldwide are faced with chronic T2DM, which also manifests …
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Evaluating Determinants of Mitochondrial Mutagenesis and their Intersections with Cell Fate
… are associated with neurodegenerative diseases, metabolic syndromes, cancer, and pathologies of aging; although establishing direct links between cause and consequence of mtDNA mutagenesis has remained elusive. In this thesis, I sought to directly test two possible mechanisms of somatic …
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Role of Exchange Protein Directly Activated by cAMP Isoform 1 in Energy Homeostasis
… signaling pathways are important for maintaining metabolic homeostasis. The effects of cAMP are mediated mainly by protein kinase A (PKA) and the more recently discovered exchange protein directly activated by cAMP (Epac). Epac has two isoforms, the ubiquitously expressed Epac1 and the more tissue …
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Role of Exchange Protein Directly Activated by cAMP Isoform 1 in Energy Homeostasis
… signaling pathways are important for maintaining metabolic homeostasis. The effects of cAMP are mediated mainly by protein kinase A (PKA) and the more recently discovered exchange protein directly activated by cAMP (Epac). Epac has two isoforms, the ubiquitously expressed Epac1 and the more tissue …
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Optical fibre-based minimally-invasive blood glucose monitoring system.
… diabetes mellitus one of the world’s foremost metabolic syndromes, affecting the lives of around 380 million people worldwide. Although considered incurable, adverse effects of diabetes can be controlled by tightly monitoring blood glucose levels. Several methods to accomplish this have been …
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Screening the effects of indoles on the proliferation of yeast via changes in lipid carbon flux
… of complex human diseases such as cancer, metabolic syndromes, cardiovascular diseases and neurodegenerative diseases. Many substituted indoles (i.e. 2-aryl indoles) exhibit anti-proliferative effects which has prompted the design modification for new drugs to treat proliferative diseases …
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The Effect of Alhagi maurorum Medik on Mitochondrial Function
… therapeutic targets for the treatment of several metabolic syndromes and cancer. Alhagi maurorum plant is traditionally used in several clinical conditions due to its potential anti-inflammatory, hepatoprotective and gastrointestinal effects. In this study changes in cell viability, reactive …
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A metabolomics approach for targeted isolation and production of bioactive secondary metabolites in microbial isolates from extreme environments
… There is a lack of novel effective drugs for metabolic diseases, cancer and parasite infections as well as TNF-alpha inhibitors hence; underexplored marine bacteria could be an important source for new bioactive molecules.Two strains of Muricauda ruestringensis (SBT531 and SBT587) were …
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The role of redox oscillation in circadian physiology of the suprachiasmatic nucleus and hippocampus
… and disease states, such as sleep disorders, metabolic syndromes, and cardiovascular disease. The main driver of circadian behavior is a transcription-translation feedback loop of core circadian genes. Emerging evidence suggest that metabolic oscillators also play a crucial role in circadian …
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NOTCH SIGNALING REGULATES ADIPOGENESIS AND ENERGY METABOLISM
… susceptible to obesity and its associated metabolic disorders. Obesity is resulted from malfunction of the overloaded white adipocytes, which are the primary default storage sites of energy surplus. Another two types of adipocytes can also be found in human: beige and brown adipocytes. In …
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THE METABOLIC EFFECTS OF DIET-INDUCED OBESITY AND GROWTH HORMONE TREATMENT IN LONG-LIVED MICE WITH ALTERED INSULIN AND INSULIN-LIKE GROWTH FACTOR -1 SIGNALING
… at Southern Illinois University Carbondale. THE METABOLIC EFFECTS OF DIET-INDUCED OBESITY AND GROWTH HORMONE TREATMENT IN LONG-LIVED MICE WITH ALTERED INSULIN AND INSULIN-LIKE GROWTH FACTOR -1 SIGNALING MAJOR PROFESSOR: Dr. Andrzej Bartke It is well established that high calorie diets providing …