Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 82 for “"metabolic stress"”.
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Nox4 mediates metabolic stress responses
… a wide variety of chronic skeletal muscle and metabolic-related diseases, including diabetes and sarcopenia. Even in patients with advanced skeletal muscle-related diseases, exercise is a well-established method to improve skeletal muscle mitochondrial metabolism, culminating in enhanced …
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Regulation of Metabolic Stress-Induced snoRNAs
… non-adipose tissues is associated with oxidative stress and organ dysfunction and plays an important role in diabetic complications. While a number of stress responses have been implicated, the precise molecular mechanisms linking lipid accumulation and cellular dysfunction are not fully …
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Modulation of Axonal Transmission by Metabolic Stress
… tissue is responsible for ~20% of the basal metabolic rate. This high-energy consumption predisposes neural tissue to metabolic stress that can compromise signaling and cause irreversible damage. The locust central nervous system (CNS), however, has adaptive mechanisms for surviving metabolic …
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Indices of metabolic stress following resistance exercise
1 PDF file (ix, 91 pages)
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The Role Of Crebh In Hepatic Energy Regulation Under Metabolic Stress
… in response to nutritional, hormonal, and stress signals. Hepatocyte specific, cyclic AMP responsive element-binding protein (CREBH) is a transcription factor that is preferentially expressed in the liver and localized in the endoplasmic reticulum (ER) membrane. CREBH is known to be …
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Platiscity of C. Elegans Germline Stem Cells Under Nutritional and Metabolic Stress
… understanding how stem cells are regulated under stress is imperative. When confronted with acute starvation, stem cells must conserve energy and metabolites to cope with the lack of an external source. <em>Caenorhabditis elegans</em> germline stem cells (GSCs) are an excellent model for studying …
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UNDERSTADING THE ROLE OF PSEUDOKINASE TRB3 IN CANCER PROGRESSION AND CHEMORESISTANCE DURING METABOLIC STRESS
… revealed that Trb3 is also involved in diabetes, stress-response, and development. Previously, Trb3 upregulation was detected in certain types of cancer but its function remains unknown. The goal of our study is to gain a better understanding of the biological function of Trb3 in cancer, including …
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Role of GPS2 in the regulation and maintenance of adipose tissue physiology and function under metabolic stress and obesity
Obesity, Type 2 Diabetes, and metabolic stress are systemic health issues that result from dysfunctions of white adipose tissue (WAT). As an endocrine organ, WAT is often possessed of a high degree of plasticity, capable of matching the metabolic conditions of which it is presented and responsible …
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Examining Sex Differences in Substrate Utilization During Threshold-Based Exercise Prescription
… [%VO2max]) elicits sex specific amounts of metabolic stress and ratios of carbohydrate to fat oxidation that result in a lower steady-state respiratory exchange ratio (RER) in females. Differences in exercise response may be explained by differences in metabolic stress and muscle oxygenation …
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A Novel Protective Role for p130 in Neuron Oxidative Stress
… phosphorylation. Conditions of increased metabolic stress or treatment of neurons with ROS inducing agent resulted in mitochondrial localization of p130 in neurons. In the mitochondria, p130 bound to mitochondrial DNA and was associated with decreased mitochondrial gene expression. This …
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The Effects of Carbohydrate Mouth Rinse on Fasted High-Intensity Interval Training in Recreationally Trained Individuals
… state by allowing the accumulation of greater metabolic stress, and thus physiological adaptations, for no increased perceptual cost. The greater metabolic stress may be the result of more work being completed in the first interval, however the sample size was insufficient to fully determine …
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Nutritional Support of the Critically Ill Pediatric Patient : Foundations and Controversies
… Critical illness is associated with significant metabolic stress. It is crucial to understand the physiological response to stress to create nutritional recommendations for critically ill pediatric patients in the PICU.
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Paediatric burn wound patients: blood transfusion and requirements in the peri-operative period
… excision can be deceptively large, as can the metabolic stress associated with large surgical procedures performed in the post-burn period (3).
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Central and peripheral fatigue in response to the acute and chronic metabolic demand: implications for exercise tolerance
… which are influenced by exercise-induced metabolic stress. Developments in non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS), have allowed for measurement of central nervous system (CNS) processes alongside measurements of muscle performance and …
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FUNCTIONAL DISSECTION OF ADIPOKINETIC HORMONE PRODUCING CELLS
The mechanisms of how organisms maintain metabolic homeostasis in light of significant environmental variation in food availability are not completely understood. In Drosophila, the mobilization of energy is primarily controlled by the endocrine factor Adipokinetic Hormone (AKH). AKH function is …
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Modulation as an Acidosis-Evoked Current by A1 Adenosine Receptors in the CA1 Region of the Mouse Hippocampus
… with hypoxia and hypoglycemia are immediate metabolic consequences of reduced blood flow to the brain. Acidosis exacerbates ischemic brain injury by activating non-selective cation currents that induce neuronal damage in a calcium-dependent manner, independent of glutamate receptor …
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INVESTIGATION OF MONGOLIAN SEA BUCKTHORN ((Hippophae rhamnoides spp. Mongolica) - NUTRITIONAL STUDY -
… in sugar manipulation experiments to simulate metabolic stress conditions. The sea buckthorn supplementation improved developmental outcomes in the flies with high sugar diets, implying protective antioxidative or metabolic effects. Furthermore, a functional food product was developed using the …
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A peptidomic investigation into enteroendocrine cells and islets of humans and mice
… is the islet peptidome altered in response to metabolic stress. I therefore carried out an investigation to address these questions. Targeted LC-MS methodology was used to search for intra-islet GLP1 receptor agonists. No peptides derived from glucose-dependent insulinotropic polypeptide (GIP) …
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Synthesis towards synthetic adenosine receptor
… in the extracellular space in response to metabolic stress and cell damage, and elevations in extracellular adenosine level are found in conditions like myocardial ischemia, hypoxia, inflammation and trauma. Its abnormal concentration therefore could be a marker of many diseases. Therefore …
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